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C5AR1 抗体

C5AR1 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272007
发货至: 中国
  • 抗原 See all C5AR1 抗体
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    适用
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    人, 小鼠
    宿主
    • 79
    • 28
    • 17
    • 1
    • 1
    克隆类型
    • 79
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    • 2
    多克隆
    标记
    • 59
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    This C5AR1 antibody is un-conjugated
    应用范围
    • 69
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of D88/C5aR protein. (region surrounding Ser334)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity-Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product C5AR1 Primary Antibody
  • 应用备注
    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    别名
    CD88 / C5R1 (C5AR1 产品)
    别名
    C5A antibody, C5AR antibody, C5R1 antibody, CD88 antibody, C5aR antibody, C5r1 antibody, Cd88 antibody, D7Msu1 antibody, GPR77 antibody, complement C5a receptor 1 antibody, complement component 5a receptor 1 antibody, C5AR1 antibody, C5ar1 antibody, c5ar1 antibody
    背景
    The human anaphylatoxin C5a is a 74 residue glycopeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a can be demonstrated, rendering this molecule an important mediartor of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP binding coupled receptor that belongs to the rhodopsin supergene family. C5a receptor 1 expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. ESTs have been isolated from B cell/lung/testis, nerve, and placenta libraries.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1
    分子量
    approx. 45 kDa
    基因ID
    728
    NCBI登录号
    NP_001727
    UniProt
    P21730
    途径
    Complement System
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