C5AR1 抗体
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Quick Overview for C5AR1 抗体 (ABIN272007)
抗原
See all C5AR1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of D88/C5aR protein. (region surrounding Ser334)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity-Chromatography using epitope-specific immunogen
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anti-Complement Component 5a Receptor 1 (C5AR1) (C-Term) antibody
Verified C5AR1 适用: 人 WB, FACS, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 250-350) antibodyC5AR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 1-350) antibodyC5AR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E2 unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 15-27), (N-Term) antibodyC5AR1 适用: 人, Cow, 兔, 雪貂 WB, FACS, IHC (p), IP 宿主: 小鼠 Monoclonal S5-1 unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 1-36) antibodyC5AR1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) antibodyC5AR1 适用: 人, 兔 FACS, IHC, IHC (p), Func, Neut 宿主: 小鼠 Monoclonal unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 1-350) antibodyC5AR1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 1-350) antibodyC5AR1 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 15-27), (N-Term) antibody (APC)C5AR1 适用: 人, Cow, 兔, 雪貂 FACS 宿主: 小鼠 Monoclonal S5-1 APC
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 15-27), (N-Term) antibody (PE)C5AR1 适用: 人, Cow, 兔, 雪貂 FACS 宿主: 小鼠 Monoclonal S5-1 PE
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应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
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别名
- CD88 / C5R1
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背景
- The human anaphylatoxin C5a is a 74 residue glycopeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a can be demonstrated, rendering this molecule an important mediartor of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP binding coupled receptor that belongs to the rhodopsin supergene family. C5a receptor 1 expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. ESTs have been isolated from B cell/lung/testis, nerve, and placenta libraries.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1
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分子量
- approx. 45 kDa
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基因ID
- 728
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NCBI登录号
- NP_001727
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UniProt
- P21730
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途径
- Complement System
抗原
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