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UBA2 抗体

The 兔 多克隆 anti-UBA2 antibody (ABIN271971) specifically detects UBA2 in WB, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN271971
发货至: 中国
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Quick Overview for UBA2 抗体 (ABIN271971)

抗原

See all UBA2 抗体
UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

适用

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宿主

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克隆类型

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多克隆

标记

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This UBA2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Uba2 protein. (region surrounding Ser621)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

    别名

    SAE2 / UBA2

    背景

    The human UBiquitin Activating domain 2 (UBA2) gene is located on chromosome 19q12. Human UBA2 could form a beta mercaptoethanol-sensitive conjugate with members of the sentrin family, but not with ubiquitin of NEDD8 in the presence of AOS1. The recombinant proteins, Sua1p and hUba2, form a complex. In this complex, hUba2 binds SUMO-1, which gives the complex the activity of the SUMO-1 activating enzyme. Therefore, UBA2 has been found to be a component of the sentrin-activating enzyme complex.Synonyms: ARX, Anthracycline-associated resistance ARX, HRIHFB2115, SUMO-activating enzyme subunit 2, UBLE1B, Ubiquitin-like 1-activating enzyme E1B

    分子量

    approx. 71 kDa

    基因ID

    10054

    NCBI登录号

    NP_005490

    UniProt

    Q9UBT2
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