DOK7 抗体
Quick Overview for DOK7 抗体 (ABIN2719664)
抗原
See all DOK7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens docking protein 7 (DOK7), transcript variant 1
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human DOK7(NP_775931) produced in HEK293T cell.
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亚型
- IgG2b
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应用备注
- WB 1:2000, FLOW 1:100,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- DOK7 (Docking Protein 7 (DOK7))
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别名
- DOK7
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背景
- The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
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分子量
- 52.9 kDa
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基因ID
- 285489
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NCBI登录号
- NM_173660
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HGNC
- 285489
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途径
- Skeletal Muscle Fiber Development
抗原
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