BCAR1 抗体
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北京 101111
Quick Overview for BCAR1 抗体 (ABIN271903)
抗原
See all BCAR1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of p130 Cas protein. (region surrounding Val404)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (AA 1-240) antibody
BCAR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) antibodyBCAR1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) antibodyBCAR1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (pTyr410) antibodyBCAR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (AA 68-218) antibodyBCAR1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (Internal Region) antibodyBCAR1 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (Tyr410) antibodyBCAR1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (pTyr410) antibodyKD Validated BCAR1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3870 unconjugated Recombinant Antibody
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) antibodyKD Validated BCAR1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3690 unconjugated Recombinant Antibody
anti-Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (AA 1-870) antibodyBCAR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))
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别名
- BCAR1 / CRKAS
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背景
- The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.Synonyms: Breast cancer anti-estrogen resistance protein 1, CASS1, CRK-associated substrate, Cas scaffolding protein family member 1, p130cas, p130cas
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分子量
- approx. 130 kDa
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基因ID
- 9564
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NCBI登录号
- NP_001164185
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UniProt
- P56945
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
抗原
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