Ephrin B1 抗体
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Quick Overview for Ephrin B1 抗体 (ABIN271886)
抗原
See all Ephrin B1 (EFNB1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Ephrin-B protein. (region surrounding Gln324)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Also reacts to: Ephrin-B2 -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Ephrin B1 (EFNB1) (AA 28-237) antibody
EFNB1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr324) antibodyEFNB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (AA 88-116) antibodyEFNB1 适用: 人 WB 宿主: 兔 Polyclonal RB42526 unconjugated
anti-Ephrin B1 (EFNB1) (pTyr324), (pTyr329) antibodyEFNB1 适用: 人 WB, ELISA, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (Ser312) antibodyEFNB1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (AA 179-228) antibodyEFNB1 适用: 人, 小鼠, 犬, 猴, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (AA 259-346) antibodyEFNB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) antibodyEFNB1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr330) antibodyEFNB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin B1 (EFNB1) (pTyr317) antibodyEFNB1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Ephrin B1 (EFNB1)
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别名
- Ephrin-B1
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背景
- Ephrins, which act as ligands for Eph receptors, are cell-surface proteins which fall into two categories, ephrin-A and ephrin-B based on their structure and function. Ephrin-B proteins are transmembrane and have conserved cytoplasmic tyrosine residues that are phosphorylated upon interaction with an EphB receptor. Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development.Synonyms: CEK5 LIgand, CEK5-L, EFL-3, EFL3, EFNB1, ELK-L, EPH-related receptor tyrosine kinase ligand 2, EPLG2, LERK-2, LERK2
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分子量
- approx. 59 kDa
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基因ID
- 1947
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NCBI登录号
- NP_004420
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UniProt
- P98172
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途径
- RTK signaling
抗原
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