Amylin/DAP 抗体
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Quick Overview for Amylin/DAP 抗体 (ABIN271869)
抗原
See all Amylin/DAP (IAPP) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Amylin protein. (region surrounding His28)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Islet Amyloid Polypeptide (IAPP) antibody
IAPP 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (Internal Region) antibodyIAPP 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) antibodyIAPP 适用: 人 IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal R10-99 unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (AA 1-89) antibodyIAPP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (AA 34-70) antibodyIAPP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (N-Term) antibodyIAPP 适用: 人, 兔, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (N-Term) antibodyIAPP 适用: 人, 大鼠, 小鼠, 兔 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) antibodyIAPP 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (N-Term) antibodyIAPP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (AA 10-90) antibodyIAPP 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
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别名
- Amylin / IAPP
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背景
- Adrenomedullin (AM), alpha- and beta-calcitonin gene-related peptide(CGRP), calcitonin (CT), and amylin are homologous polypeptides with overlapping biological actions such as vasodilatation and inhibition of bone resorption. Amylin (Islet/insulinoma amyloid polypeptide or IAPP) is a 37-amino acid monomeric polypeptide isolated from pancreatic amyloid. This protein, with a calculated molecular mass of 4 kDa, is a major component of amyloid-rich pancreatic extracts of three type 2 diabetic patients. IAPP has cysteine residues in positions 2 and 7, a feature found in all known calcitonin gene-related peptides. IAPP shows 46 % amino acid sequence homology with CGRP II. Since IAPP has been demonstrated immunochemically in normal beta cells of several mammals, it probably has an important role in respect to pancreatic islet function.Synonyms: Diabetes-associated peptide, Insulinoma amyloid peptide, Islet amyloid polypeptide
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分子量
- approx. 10 kDa
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基因ID
- 3375
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NCBI登录号
- NP_000406
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UniProt
- P10997
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途径
- Hormone Activity, Feeding Behaviour
抗原
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