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beta Synuclein 抗体

The 兔 多克隆 anti-beta Synuclein antibody (ABIN271836) specifically detects beta Synuclein in WB, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN271836
发货至: 中国
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Quick Overview for beta Synuclein 抗体 (ABIN271836)

抗原

See all beta Synuclein (SNCB) 抗体
beta Synuclein (SNCB) (Synuclein, beta (SNCB))

适用

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人, 小鼠, 大鼠

宿主

  • 47
  • 6
  • 1
  • 1

克隆类型

  • 51
  • 4
多克隆

标记

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  • 4
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This beta Synuclein antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Synuclein beta protein. (region surrounding Ser118)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    beta Synuclein (SNCB) (Synuclein, beta (SNCB))

    别名

    beta-Synuclein / SCNB

    背景

    The synuclein family members, including alpha-synuclein (also designated NACP for non-beta amyloid component) and beta-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. alpha-synuclein is localized to neuronal cell bodies and synapses. alpha-synuclein was first identified as a component of Alzheimers disease amyloid plaques. Abnormal platelet function in Alzheimers disease has been demonstrated. During megakaryocytic differentiation alpha-synuclein was found to be upregulated, while beta-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of alpha-synuclein has been found in patients with early onset Parkinsons disease.Synonyms: Synuclein beta

    分子量

    approx. 14 kDa

    基因ID

    6620

    NCBI登录号

    NP_001001502

    UniProt

    Q16143
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