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beta Synuclein 抗体

SNCB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7182802
发货至: 中国
  • 抗原 See all beta Synuclein (SNCB) 抗体
    beta Synuclein (SNCB) (Synuclein, beta (SNCB))
    适用
    • 50
    • 32
    • 32
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 57
    • 6
    • 1
    • 1
    • 1
    克隆类型
    • 62
    • 4
    多克隆
    标记
    • 31
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This beta Synuclein antibody is un-conjugated
    应用范围
    • 36
    • 27
    • 25
    • 14
    • 14
    • 12
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from Human Synuclein beta antibody.
    亚型
    IgG
  • 应用备注
    WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    beta Synuclein (SNCB) (Synuclein, beta (SNCB))
    别名
    SNCB (SNCB 产品)
    别名
    AI838531 antibody, betaSYN antibody, zgc:66343 antibody, sncb antibody, MGC75784 antibody, LOC619281 antibody, SNCB antibody, syub antibody, synuclein beta antibody, synuclein, beta antibody, synuclein beta L homeolog antibody, Beta-synuclein antibody, SNCB antibody, Sncb antibody, sncb antibody, sncb.L antibody, syub antibody
    背景

    Background: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

    Yuxin Fan, Hum. Mol. Genet., Oct 2006, 15: 3002 - 3011.
    Makoto Hashimoto, J. Biol. Chem., May 2004, 279: 23622 - 23629.
    Cristine Alves da Costa, J. Biol. Chem., Sep 2003, 278: 37330 - 37335.
    Heather Snyder, J. Biol. Chem., Mar 2005, 280: 7562 - 7569.

    Aliases: 14 kDa brain-specific protein antibody, Beta-synuclein antibody, Phosphoneuroprotein 14 antibody, PNP14 antibody, Sncb antibody, Synuclein beta antibody, SYUB_HUMAN antibody

    UniProt
    Q16143
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