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PSCA 抗体

This 兔 多克隆 antibody specifically detects PSCA in WB 和 EIA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN271792
发货至: 中国
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Quick Overview for PSCA 抗体 (ABIN271792)

抗原

See all PSCA 抗体
PSCA (Prostate Stem Cell Antigen (PSCA))

适用

  • 76
  • 18
  • 13
  • 2
  • 2
  • 2
人, 小鼠

宿主

  • 51
  • 25
  • 4
  • 1

克隆类型

  • 53
  • 28
多克隆

标记

  • 44
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PSCA antibody is un-conjugated

应用范围

  • 47
  • 20
  • 13
  • 13
  • 11
  • 6
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 交叉反应 (详细)

    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.
  • 抗原

    PSCA (Prostate Stem Cell Antigen (PSCA))

    别名

    PSCA

    背景

    Prostate stem cell antigen (PSCA) is a 123 amino acid glycosylated protein that shares homology with the Thy-1/Ly-6 family of glycosyl-phosphatidylinositol GPI)-anchored cell surface antigens. The PSCA gene maps to chromosome 8q24.2 and transcripts are most prevalent in prostate and placenta. The gene encoding c-myc is also located on chromosome 8q and like PSCA, is overexpressed in a large number of prostate cancers. Transcripts for PSCA are also abundant in urothelial tumors, and levels of PSCA transcripts increase in confluent RT112 bladder carcinomas, suggesting that PSCA is a marker for urothelial and gastric tissue carcinogenesis. Among prostate cancer cell surface antigens, PSCA is expressed in over 80 % of prostate carcinomas and correlates well to certain prostate cancer phenotypes such as prostate cancer bone metastates.Synonyms: Prostate stem cell antigen

    分子量

    approx. 29 kDa

    基因ID

    9606

    UniProt

    O43653
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