Presenilin 1 抗体
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- 抗原 See all Presenilin 1 (PSEN1) 抗体
- Presenilin 1 (PSEN1)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Presenilin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Presenilin 1 protein. (region surrounding Ser28)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product PSEN1 Primary Antibody
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anti-Presenilin 1 (PSEN1) (AA 1-160) antibody
PSEN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (AA 330-359), (C-Term) antibodyPSEN1 适用: 人, 小鼠 WB, IHC (p), FACS, IF 宿主: 兔 Polyclonal RB2257 unconjugated
anti-Presenilin 1 (PSEN1) (AA 4-218) antibodyPSEN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (Middle Region) antibodyPSEN1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (AA 1-160) antibodyPSEN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (AA 1-100) antibody (FITC)PSEN1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal FITC
anti-Presenilin 1 (PSEN1) (AA 1-100) antibody (Alkaline Phosphatase (AP))PSEN1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-Presenilin 1 (PSEN1) (AA 100-200) antibody (Biotin)PSEN1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal Biotin
anti-Presenilin 1 (PSEN1) (AA 100-200) antibody (PE)PSEN1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal PE
anti-Presenilin 1 (PSEN1) (AA 1-100) antibody (APC)PSEN1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal APC
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- 应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- Presenilin 1 (PSEN1)
- 别名
- Presenilin-1 (PSEN1 产品)
- 别名
- pre1 antibody, psen antibody, zfPS1 antibody, zf-PS1 antibody, ad3 antibody, fad antibody, ps1 antibody, s182 antibody, X-PS-beta antibody, X-PS-alpha antibody, AD3 antibody, FAD antibody, PS-1 antibody, PS1 antibody, S182 antibody, Ad3h antibody, presenilin 1 antibody, presenilin 1 L homeolog antibody, psen1 antibody, PSEN1 antibody, Psen1 antibody, psen1.L antibody
- 背景
- A novel protein, designated Presenilin 1 (also designated S182) and mapping to the AD3 locus of chromosome 14q24.3, has been described. Mutations in the gene encoding Presenilin 1 have been found in families suffering from early-onset Alzheimer's disease. A highly related protein, designated Presenilin 2 (also designated STM2), shares 80 % amino acid sequence identity with Presenilin 1. Presenilin 1 and Presenilin 2 have similar structures and represent novel members of the seven-pass transmembrane receptor superfamily. Point mutations in the gene encoding Presenilin 2 have been found in Volga German families who suffer from an inherited form of early-onset Alzheimer's disease. Whether these proteins function as ligand-gated ion channels or G protein-coupled receptors has yet to be resolved. ALG-3, the mouse homolog of human Presenilin 2, has been cloned from the mouse liver cDNA library.Synonyms: AD3, AF3, Alzheimer Disease 3, FAD, PS-1, PS1, PSEN1, PSNL1, Presenilin 1, S182
- 分子量
- 22, 55 kDa
- 基因ID
- 5663
- NCBI登录号
- NP_000012
- UniProt
- P49768
- 途径
- Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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