CDKN2B 抗体
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北京 101111
Quick Overview for CDKN2B 抗体 (ABIN271760)
抗原
See all CDKN2B 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of p15 INK protein. (region surrounding Gly113)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B) antibody
CDKN2B 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 8H4 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B) (AA 102-130) antibodyCDKN2B 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B) antibodyCDKN2B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B) (AA 102-130), (C-Term) antibodyCDKN2B 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB13822 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B) antibodyCDKN2B 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B) (AA 1-130) antibodyCDKN2B 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B) (AA 1-138) antibodyCDKN2B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8C4 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B) (AA 1-138) antibodyCDKN2B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B) (Internal Region) antibodyCDKN2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B) (AA 1-138) antibodyCDKN2B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA: 1/5000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50-1/200Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
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别名
- CDKN2B / p15INK4b
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背景
- The normal progression of cells through the cell cycle is under the control of the cyclin dependent protein kinases Cdk4 and Cdk6 which are subject to inhibition by the mitotic inhibitory protein, p16. An isolated member of the p16 family has been designated p15. p15 expression is upregulated approximately 30-fold in TGFβ-treated human keratinocytes, suggesting that p15 may act as an effector of TGFβ-mediated cell cycle arrest. The gene encoding p15 has been mapped to chromosome 9p21 at a position adjacent to the p16 gene at a site of frequent chromosomal abnormality in human tumors. It has been suggested that p15 may function as an effector of TGFβ-mediated cell cycle arrest through inhibition of Cdk4 and Cdk6 kinases.Synonyms: Cyclin-dependent kinase 4 inhibitor B, MTS2, Multiple tumor suppressor 2, p14-INK4b, p14INK4b, p15-INK4b
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分子量
- approx. 15 kDa
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基因ID
- 1030
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NCBI登录号
- NP_004927
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UniProt
- P42772
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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