Annexin A3 抗体
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北京 101111
Quick Overview for Annexin A3 抗体 (ABIN2716166)
抗原
See all Annexin A3 (ANXA3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens annexin A3 (ANXA3)
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human ANXA3 (NP_005130) produced in HEK293T cell.
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亚型
- IgG2b
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应用备注
- WB 1:500~2000, IHC 1:150,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Overexpression of ANXA3 is an independent prognostic indicator in gastric cancer and its depletion suppresses cell proliferation and tumor growth." in: Oncotarget, Vol. 7, Issue 52, pp. 86972-86984, (2018) (PubMed).
: "Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 54, Issue 8, pp. 598-607, (2015) (PubMed).
: "Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 2, pp. 354-66, (2015) (PubMed).
: "Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers." in: PLoS ONE, Vol. 9, Issue 2, pp. e88168, (2014) (PubMed).
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- Annexin A3 (ANXA3)
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别名
- ANXA3
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背景
- This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
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分子量
- 36.2 kDa
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基因ID
- 306
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NCBI登录号
- NM_005139
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HGNC
- 306
抗原
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