OPRD1 抗体 (AA 81-180) (Biotin)
Quick Overview for OPRD1 抗体 (AA 81-180) (Biotin) (ABIN2690092)
抗原
See all OPRD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-180
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特异性
- This antibody may also have a weak secondary cross-reaction with Mu-type opioid receptor, which is primarily expressed in the adrenal gland and testis. This is predicted based upon a 79 % non-contiguous sequence similarity.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human OPRD1
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亚型
- IgG
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- OPRD1 (Opioid Receptor, delta 1 (OPRD1))
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别名
- Delta-type opioid receptor
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背景
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Synonyms: OPRD, Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1
Background: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
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基因ID
- 4985
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UniProt
- P41143
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途径
- Protein targeting to Nucleus
抗原
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