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OPRD1 抗体 (AA 81-180)

OPRD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2690091
发货至: 中国
  • 抗原 See all OPRD1 抗体
    OPRD1 (Opioid Receptor, delta 1 (OPRD1))
    抗原表位
    • 19
    • 14
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-180
    适用
    • 64
    • 50
    • 48
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 63
    • 1
    • 1
    克隆类型
    • 55
    • 10
    多克隆
    标记
    • 29
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This OPRD1 antibody is un-conjugated
    应用范围
    • 50
    • 25
    • 25
    • 16
    • 16
    • 11
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC)
    特异性
    This antibody may also have a weak secondary cross-reaction with Mu-type opioid receptor, which is primarily expressed in the adrenal gland and testis. This is predicted based upon a 79 % non-contiguous sequence similarity.
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human OPRD1
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Wu, Li, Wu: "The effect of chronic intermittent hypoxia on respiratory sensitivity to morphine in rats." in: Sleep & breathing = Schlaf & Atmung, Vol. 21, Issue 1, pp. 227-233, (2017) (PubMed).

  • 抗原
    OPRD1 (Opioid Receptor, delta 1 (OPRD1))
    别名
    Delta-type opioid receptor (OPRD1 产品)
    别名
    OPRD antibody, DOR-1 antibody, Nbor antibody, mDOR antibody, opioid receptor delta 1 antibody, opioid receptor, delta 1 antibody, OPRD1 antibody, Oprd1 antibody
    背景

    Synonyms: OPRD, Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1

    Background: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

    基因ID
    4985
    UniProt
    P41143
    途径
    Protein targeting to Nucleus
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