(4 references)-
- 抗原 See all TACSTD2 抗体
- TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TACSTD2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Trop-2/GA733-1 is a cell surface glycoprotein that was originally identified on human trophoblast and choriocarcinoma cell lines and has been shown to be expressed in most human carcinomas. Trop-2 has been cloned and shown to encode a type-1 transmembrane protein with a single transmembrane domain. Furthermore, research has shown Trop-2 to be involved in the transduction of an intracellular calcium signal, although the exact physiological mechanism has yet to be elucidated. Flow cytometric analysis of Trop-2. MCF7 cells (Human breast adenocarcinoma, ATCC HTB-22) were incubated with 0.25 μg of the Purified Mouse Anti-Human Trop-2 antibody (clone 162-46, shaded) or with a mouse IgG1 isotype control (Cat. No. 555746, unshaded) in BD Pharmingen™ Stain Buffer (Cat. No.554656) for 1 hr on ice. Cells were washed twice in Stain Buffer and incubated with 1 μg of a FITC Goat Anti-Mouse Ig secondary antibody (Cat. No.554001) in Stain Buffer for 1 hr on ice. Cells were washed twice and analyzed by flow cytometry.
BD Pharmingen™ Purified Mouse Anti-Human Trop-2 - Purified - Clone 162-46 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human BeWo (choriocarcinoma) Cell Line
- 克隆位点
- 162
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TACSTD2 Primary Antibody
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anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 31-274) antibody
TACSTD2 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal TACSTD2-2152 unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) antibodyTACSTD2 适用: 人 WB, IHC, FACS, IF 宿主: 兔 Monoclonal unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 31-274) antibodyTACSTD2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal TACSTD2-2151 unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) antibodyTACSTD2 适用: 人, Pig WB, IHC, FACS, ICC 宿主: 小鼠 Monoclonal TrMab-6 unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 27-270) antibodyTACSTD2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Internal Region) antibodyTACSTD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 27-274) antibodyTACSTD2 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM74 unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 31-274) antibodyTACSTD2 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-733R unconjugated Recombinant Antibody
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 221-322) antibodyTACSTD2 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Internal Region) antibodyVerified TACSTD2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Aberrant CCND1 copies and cyclin D1 mRNA expression do not result in the production of functional cyclin D1 protein in anaplastic large cell lymphoma." in: Histology and histopathology, Vol. 24, Issue 8, pp. 1035-48, (2009) (PubMed).
: "Human Trop-2 is a tumor-associated calcium signal transducer." in: International journal of cancer. Journal international du cancer, Vol. 76, Issue 5, pp. 671-6, (1998) (PubMed).
: "Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas." in: International journal of cancer. Journal international du cancer, Vol. 62, Issue 5, pp. 610-8, (1995) (PubMed).
: "Human trophoblast cell-surface antigens defined by monoclonal antibodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 78, Issue 8, pp. 5147-50, (1982) (PubMed).
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: "Aberrant CCND1 copies and cyclin D1 mRNA expression do not result in the production of functional cyclin D1 protein in anaplastic large cell lymphoma." in: Histology and histopathology, Vol. 24, Issue 8, pp. 1035-48, (2009) (PubMed).
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- 抗原
- TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
- 别名
- Trop-2 (TACSTD2 产品)
- 别名
- EGP-1 antibody, EGP1 antibody, GA733-1 antibody, GA7331 antibody, GP50 antibody, M1S1 antibody, TROP2 antibody, C80403 antibody, Ly97 antibody, Prp1 antibody, tumor associated calcium signal transducer 2 antibody, tumor-associated calcium signal transducer 2 antibody, TACSTD2 antibody, Tacstd2 antibody
- 背景
- Synonyms: GA733-1
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