TACSTD2 抗体
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北京 101111
Quick Overview for TACSTD2 抗体 (ABIN2689944)
抗原
See all TACSTD2 抗体适用
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克隆类型
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应用范围
克隆位点
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产品特性
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Trop-2/GA733-1 is a cell surface glycoprotein that was originally identified on human trophoblast and choriocarcinoma cell lines and has been shown to be expressed in most human carcinomas. Trop-2 has been cloned and shown to encode a type-1 transmembrane protein with a single transmembrane domain. Furthermore, research has shown Trop-2 to be involved in the transduction of an intracellular calcium signal, although the exact physiological mechanism has yet to be elucidated. Flow cytometric analysis of Trop-2. MCF7 cells (Human breast adenocarcinoma, ATCC HTB-22) were incubated with 0.25 μg of the Purified Mouse Anti-Human Trop-2 antibody (clone 162-46, shaded) or with a mouse IgG1 isotype control (Cat. No. 555746, unshaded) in BD Pharmingen™ Stain Buffer (Cat. No.554656) for 1 hr on ice. Cells were washed twice in Stain Buffer and incubated with 1 μg of a FITC Goat Anti-Mouse Ig secondary antibody (Cat. No.554001) in Stain Buffer for 1 hr on ice. Cells were washed twice and analyzed by flow cytometry.
BD Pharmingen™ Purified Mouse Anti-Human Trop-2 - Purified - Clone 162-46 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human BeWo (choriocarcinoma) Cell Line
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亚型
- IgG1 kappa
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anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) antibody
TACSTD2 适用: 人 WB, IHC, FACS, IF 宿主: 兔 Monoclonal unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 31-274) antibodyTACSTD2 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal TACSTD2-2152 unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 31-274) antibodyTACSTD2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal TACSTD2-2151 unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 27-270) antibodyTACSTD2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) antibodyTACSTD2 适用: 人, Pig WB, IHC, FACS, ICC 宿主: 小鼠 Monoclonal TrMab-6 unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 31-274) antibodyTACSTD2 适用: 人 IHC 宿主: 兔 Monoclonal 733R unconjugated Recombinant Antibody
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Internal Region) antibodyTACSTD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) antibodyKD Validated TACSTD2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4505 unconjugated Recombinant Antibody
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 221-322) antibodyTACSTD2 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Internal Region) antibodyVerified TACSTD2 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Aberrant CCND1 copies and cyclin D1 mRNA expression do not result in the production of functional cyclin D1 protein in anaplastic large cell lymphoma." in: Histology and histopathology, Vol. 24, Issue 8, pp. 1035-48, (2009) (PubMed).
: "Human Trop-2 is a tumor-associated calcium signal transducer." in: International journal of cancer. Journal international du cancer, Vol. 76, Issue 5, pp. 671-6, (1998) (PubMed).
: "Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas." in: International journal of cancer. Journal international du cancer, Vol. 62, Issue 5, pp. 610-8, (1995) (PubMed).
: "Human trophoblast cell-surface antigens defined by monoclonal antibodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 78, Issue 8, pp. 5147-50, (1982) (PubMed).
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: "Aberrant CCND1 copies and cyclin D1 mRNA expression do not result in the production of functional cyclin D1 protein in anaplastic large cell lymphoma." in: Histology and histopathology, Vol. 24, Issue 8, pp. 1035-48, (2009) (PubMed).
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- TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
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别名
- Trop-2
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背景
- Synonyms: GA733-1
抗原
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