TCR beta 抗体
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北京 101111
Quick Overview for TCR beta 抗体 (ABIN2689917)
抗原
See all TCR beta 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
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The H57-597 antibody reacts with a common epitope of the β chain of the T-cell Receptor (TCR) complex on αβ TCR-expressing thymocytes and peripheral T lymphocytes and NK1.1+ thymocytes and NK-T cells of all mouse strains tested. It does not react with γδTCR-bearing T cells. In the fetal and adult thymus, the TCR βchain may form homodimers or pair with the pre-TCR achain on the surface of immature thymocytes before expression of the TCR achain. Plate-bound or soluble H57-597 antibody activates αβTCR-bearing T cells, and plate-bound mAb can induce apoptotic death. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.
BD Pharmingen™ Purified Hamster Anti-Mouse TCR β Chain - Purified - Clone H57-597 - Isotype Armenian Hamster IgG2, λ1 - Reactivity Ms - 0.5 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- TCR affinity-purified from mouse T-cell hybridoma DO-11.10
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亚型
- IgG2 lambda
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anti-T Cell Receptor (TCR) beta (TCR beta) antibody (FITC)
TCR beta 适用: 小鼠 FACS 宿主: Armenian Hamster Monoclonal H57-597 FITC
anti-T Cell Receptor (TCR) beta (TCR beta) antibody (APC)TCR beta 适用: 小鼠 FACS 宿主: Armenian Hamster Monoclonal H57-597 APC
anti-T Cell Receptor (TCR) beta (TCR beta) (Internal Region) antibodyTCR beta 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-T Cell Receptor (TCR) beta (TCR beta) antibodyTCR beta 适用: 小鼠 FACS, IP 宿主: 仓鼠 Monoclonal H57-597 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Different initiation of pre-TCR and gammadeltaTCR signalling." in: Nature, Vol. 406, Issue 6795, pp. 524-7, (2000) (PubMed).
: "Mouse NK1.1+ T cells: a new family of T cells." in: Immunology today, Vol. 17, Issue 2, pp. 71-6, (1996) (PubMed).
: "Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2." in: The Journal of experimental medicine, Vol. 184, Issue 5, pp. 1631-8, (1996) (PubMed).
: "Diversity of V gamma gene segments rearranged to the J gamma 4 gene in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 2, pp. 676-84, (1995) (PubMed).
: "Rapid rejection of H2k and H2k/b bone marrow cell grafts by CD8+ T cells and NK cells in irradiated mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 8, pp. 3742-9, (1995) (PubMed).
: "Gamma delta T cells function in cell-mediated immunity to acute blood-stage Plasmodium chabaudi adami malaria." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 8, pp. 3985-90, (1995) (PubMed).
: "A subset of CD4+ thymocytes selected by MHC class I molecules." in: Science (New York, N.Y.), Vol. 263, Issue 5154, pp. 1774-8, (1994) (PubMed).
: "Preferential usage of the Fc receptor gamma chain in the T cell antigen receptor complex by gamma/delta T cells localized in epithelia." in: The Journal of experimental medicine, Vol. 179, Issue 1, pp. 365-9, (1994) (PubMed).
: "Analysis and expression of a cloned pre-T cell receptor gene." in: Science (New York, N.Y.), Vol. 266, Issue 5188, pp. 1208-12, (1994) (PubMed).
: "T cell receptor beta chain dimers on immature thymocytes from normal mice." in: European journal of immunology, Vol. 23, Issue 6, pp. 1393-6, (1993) (PubMed).
: "Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 971-84, (1993) (PubMed).
: "Phenotypic complexity of intraepithelial lymphocytes of the small intestine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 6, pp. 1746-51, (1991) (PubMed).
: "Transgenic mice demonstrate that epithelial homing of gamma/delta T cells is determined by cell lineages independent of T cell receptor specificity." in: The Journal of experimental medicine, Vol. 171, Issue 4, pp. 1015-26, (1990) (PubMed).
: "Transport and secretion of truncated T cell receptor beta-chain occurs in the absence of association with CD3." in: The Journal of biological chemistry, Vol. 265, Issue 16, pp. 9296-301, (1990) (PubMed).
: "Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 8, pp. 2736-42, (1989) (PubMed).
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: "Different initiation of pre-TCR and gammadeltaTCR signalling." in: Nature, Vol. 406, Issue 6795, pp. 524-7, (2000) (PubMed).
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- TCR beta (T Cell Receptor (TCR) beta (TCR beta))
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别名
- TCR beta Chain
抗原
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