Ly6C 抗体 (Biotin)
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北京 101111
Quick Overview for Ly6C 抗体 (Biotin) (ABIN2689822)
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产品特性
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The AL-21 antibody reacts with a non-polymorphic determinant of Ly-6C, a 14- 17- kDa GPI-linked cell-surface antigen found on some monocyte/macrophage populations, granulocytes, endothelial cells, plasma cells, and thymocyte, NK-cell, and T-subsets. Mice with the Ly-6.2 alloantigen (eg, AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129) have subsets of CD8+ and CD4+ Ly-6C+ T cells, while Ly-6.1 strains (eg, A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+ Ly-6C+ T cells. Upregulation of Ly-6C expression on CD8+ T cells by interferons α and β and poly (I:C) has been described, and Ly-6C is a memory marker on CD8+ T cells.
BD Pharmingen™ Biotin Rat Anti-Mouse Ly-6C - Biotin - Clone AL-21 - Isotype Rat IgM, κ - Reactivity Ms - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Not reported
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亚型
- IgM kappa
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anti-Ly-6C (Ly-6C) antibody
Ly-6C 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal HK1-4 unconjugated
anti-Ly-6C (Ly-6C) antibodyLy-6C 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ly-6C (Ly-6C) antibody (Biotin)Ly-6C 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal HK1-4 Biotin
anti-Ly-6C (Ly-6C) antibody (FITC)Ly-6C 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal HK1-4 FITC
anti-Ly-6C (Ly-6C) antibody (PE)Ly-6C 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal HK1-4 PE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Ly6C expression differentiates plasma cells from other B cell subsets in mice." in: European journal of immunology, Vol. 32, Issue 1, pp. 97-103, (2001) (PubMed).
: "In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 1, pp. 97-105, (1998) (PubMed).
: "Functional characterization of NK1.1 + Ly-6C+ cells." in: Immunology letters, Vol. 54, Issue 1, pp. 5-9, (1997) (PubMed).
: "Induction of bystander T cell proliferation by viruses and type I interferon in vivo." in: Science (New York, N.Y.), Vol. 272, Issue 5270, pp. 1947-50, (1996) (PubMed).
: "Differences in the expression of Ly-6C on neutrophils and monocytes following PI-PLC hydrolysis and cellular activation." in: Immunology letters, Vol. 41, Issue 1, pp. 49-57, (1994) (PubMed).
: "Expression of an unusual T cell receptor (TCR)-V beta repertoire by Ly-6C+ subpopulations of CD4+ and/or CD8+ thymocytes. Evidence for a developmental relationship between Ly-6C+ thymocytes and ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 9, pp. 2883-91, (1991) (PubMed).
: "Ly-6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon-gamma." in: European journal of immunology, Vol. 18, Issue 11, pp. 1819-26, (1989) (PubMed).
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- Ly6C (Ly-6C) (Ly-6C)
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别名
- Ly-6C
抗原
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