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人 Papilloma Virus 16 Capsid Protein (HPV-16 L1) 抗体

There are 4+ publications for this product available. The 小鼠 单克隆 anti-Human Papilloma Virus 16 Capsid Protein antibody is suitable to detect Human Papilloma Virus 16 Capsid Protein in samples from 人. It has been validated for IHC (f) 和 IHC (fro).
产品编号 ABIN2689560
发货至: 中国
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Quick Overview for 人 Papilloma Virus 16 Capsid Protein (HPV-16 L1) 抗体 (ABIN2689560)

抗原

Human Papilloma Virus 16 Capsid Protein (HPV-16 L1)

适用

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宿主

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小鼠

克隆类型

  • 11
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单克隆

标记

  • 12
非结合性

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

CAMVIR
  • 产品特性

    More than 60 different types of human papilloma viruses (HPVs) have been isolated. The human papilloma viruses encode three late proteins, which are produced only in terminally differentiating keratinocytes, two of which (the L1 and L2 proteins) are structural components of the virion. Virus-like particles can be assembled by over-expressing L1 and L2 in vitro, demonstrating that L1 and L2 are necessary and sufficient components of the HPV capsomeres. HPV-16 has been reported to migrate at a reduced molecular weight of ~57 kD by SDS-PAGE. The CAMVIR-1 antibody reacts with the L1 protein of HPV-16 and may also cross-react with other HPV types, such as HPV-33. Immunohistochemistry for HPV type 16. A formalin-fixed, paraffin-embedded section from human cervix infected with HPV type 16 was stained with the Purified Mouse Anti-HPV 16 L1 antibody. Cells expressing the L1 protein of the HPV 16 virus can be identifed by the intense brown labeling (magnification 20X).

    BD Pharmingen™ Purified Mouse Anti-HPV-16 L1 - Purified - Clone CAMVIR-1 - Isotype Mouse IgG2a, κ - Reactivity Hu - 1 mL

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Doorbar, Ely, Coleman, Hibma, Davies, Crawford: "Epitope-mapped monoclonal antibodies against the HPV16E1--E4 protein." in: Virology, Vol. 187, Issue 1, pp. 353-9, (1992) (PubMed).

    Zhou, Sun, Stenzel, Frazer: "Expression of vaccinia recombinant HPV 16 L1 and L2 ORF proteins in epithelial cells is sufficient for assembly of HPV virion-like particles." in: Virology, Vol. 185, Issue 1, pp. 251-7, (1991) (PubMed).

    McLean, Churcher, Meinke, Smith, Higgins, Stanley, Minson: "Production and characterisation of a monoclonal antibody to human papillomavirus type 16 using recombinant vaccinia virus." in: Journal of clinical pathology, Vol. 43, Issue 6, pp. 488-92, (1990) (PubMed).

    de Villiers: "Heterogeneity of the human papillomavirus group." in: Journal of virology, Vol. 63, Issue 11, pp. 4898-903, (1989) (PubMed).

  • 抗原

    Human Papilloma Virus 16 Capsid Protein (HPV-16 L1)

    别名

    HPV-16 L1

    物质类

    Viral Protein
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