Human Papilloma Virus 16 Capsid Protein (HPV-16 L1) 抗体
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Quick Overview for Human Papilloma Virus 16 Capsid Protein (HPV-16 L1) 抗体 (ABIN3025478)
抗原
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- HPV-16 L1 Antibody (azide and preservative free)
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产品特性
- Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33, very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.
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纯化方法
- Protein G affinity chromatography
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免疫原
- Human papilloma virus type 16, major capsid protein L1, was used as the immunogen for the HPV-16 L1 antibody.
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亚型
- IgG2a, kappa
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应用备注
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Optimal dilution of the HPV-16 L1 antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the HPV-16 L1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Human Papilloma Virus 16 Capsid Protein (HPV-16 L1)
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别名
- HPV-16 L1
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物质类
- Viral Protein
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背景
- Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33, very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.
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UniProt
- P03101
抗原
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