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Galectin 3 抗体

LGALS3 适用: 人 IHC (f), ICS 宿主: 小鼠 Monoclonal B2C10 unconjugated
产品编号 ABIN2689513
发货至: 中国
  • 抗原 See all Galectin 3 (LGALS3) 抗体
    Galectin 3 (LGALS3)
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Galectin 3 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Intracellular Staining (ICS)
    品牌
    BD Pharmingen™
    产品特性
    Reacts with Galectin-3, a 30 kDa protein, a member of a newly defined family of β-galactoside-binding animal lectins. It has been previously referred to as IgE-binding protein (εBP) and carbohydrate-binding protein 35 (CBP35). It is expressed on many tissues and cell types. Galectin-3 can be found in the nucleus and/or cytoplasm, on the cell surface and in the extra cellular matrix. Its function has been found to be diverse. It has been reported to be markedly elevated in the nucleus of proliferating cells, suggesting that Galectin-3 may play a role in cell growth regulation. Studies of Galectin-3 on the cell surface have shown it to be a non-integrin, laminin-binding protein, suggesting its role in cell adhesion to basement membranes. Monoclonal antibody B2C10 is suitable for immunohistochemical staining of parafin-embedded tissue sections. Profile of permeabilized peripheral blood monocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

    BD Pharmingen™ Purified Mouse Anti-Human Galectin-3 - Purified - Clone B2C10 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    B2C10
    亚型
    IgG1 kappa
    Top Product
    Discover our top product LGALS3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Cortegano, del Pozo, Cárdaba, de Andrés, Gallardo, del Amo, Arrieta, Jurado, Palomino, Liu, Lahoz: "Galectin-3 down-regulates IL-5 gene expression on different cell types." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 1, pp. 385-9, (1998) (PubMed).

    Liu, Hsu, Zuberi, Hill, Shenhav, Kuwabara, Chen: "Modulation of functional properties of galectin-3 by monoclonal antibodies binding to the non-lectin domains." in: Biochemistry, Vol. 35, Issue 19, pp. 6073-9, (1996) (PubMed).

    Mey, Leffler, Hmama, Normier, Revillard: "The animal lectin galectin-3 interacts with bacterial lipopolysaccharides via two independent sites." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 4, pp. 1572-7, (1996) (PubMed).

    Cherayil, Weiner, Pillai: "The Mac-2 antigen is a galactose-specific lectin that binds IgE." in: The Journal of experimental medicine, Vol. 170, Issue 6, pp. 1959-72, (1990) (PubMed).

  • 抗原
    Galectin 3 (LGALS3)
    别名
    Galectin-3 (LGALS3 产品)
    别名
    CBP 35 antibody, Gal-3 antibody, Galectin-3 antibody, leg3 antibody, galactoside-binding antibody, galectin-3 antibody, lectin antibody, soluble antibody, CBP35 antibody, GAL3 antibody, GALBP antibody, GALIG antibody, L31 antibody, LGALS2 antibody, MAC2 antibody, MGC52947 antibody, MGC75803 antibody, LGALS3 antibody, gal-3 antibody, GBP antibody, L-34 antibody, Mac-2 antibody, gal3 antibody, galectin 3 antibody, Galectin-3 antibody, avian beta-defensin 3 antibody, lectin, galactoside-binding, soluble, 3 L homeolog antibody, lectin, galactoside-binding, soluble, 3 antibody, galectin 2 antibody, lectin, galactose binding, soluble 3 antibody, LGALS3 antibody, leg3 antibody, AvBD3 antibody, lgals3.L antibody, lgals3 antibody, LGALS2 antibody, Lgals3 antibody
    物质类
    Chemical
    途径
    RTK signaling
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