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C5AR1 抗体

This anti-C5AR1 antibody is a 小鼠 单克隆 antibody detecting C5AR1 in FACS 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2689429
发货至: 中国

Quick Overview for C5AR1 抗体 (ABIN2689429)

抗原

See all C5AR1 抗体
C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

适用

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宿主

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小鼠

克隆类型

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  • 2
单克隆

标记

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This C5AR1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

D53
  • 品牌

    BD Pharmingen™

    产品特性

    Reacts with a 40 kDa polypeptide expressed on granulocytes, monocytes and macrophages. CD88 is a G type protein-coupled receptor with seven transmembrane domains. It binds to C5a, the α chain of the complement component C5. C5a is cleaved from C5 during complement activation. The binding of C5a to C5a receptor (C5aR, CD88) on granulocytes leads to various effects including shedding of selectins, upregulation of adhesion molecules, chemotaxis, granule exocytosis and activation of NADPH oxidase.

    BD Pharmingen™ Purified Mouse Anti-Human CD88 - Purified - Clone D53-1473 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Morelli, Larregina, Chuluyán, Kolkowski, Fainboim: "Expression and modulation of C5a receptor (CD88) on skin dendritic cells. Chemotactic effect of C5a on skin migratory dendritic cells." in: Immunology, Vol. 89, Issue 1, pp. 126-34, (1996) (PubMed).

  • 抗原

    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

    别名

    CD88

    背景

    Synonyms: C5a Receptor

    途径

    Complement System
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