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C5AR1 抗体

C5AR1 适用: 人 IHC (fro), IHC (f) 宿主: 兔 Monoclonal C85 unconjugated
产品编号 ABIN2689428
发货至: 中国
  • 抗原 See all C5AR1 抗体
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    适用
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    宿主
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    克隆类型
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    单克隆
    标记
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    This C5AR1 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    品牌
    BD Pharmingen™
    产品特性
    The human C5a receptor (C5aR) is expressed on granulocytes, monocytes, macrophages mast cells human cell lines of myeloid origin, and certain cell types in several organs, including dendritic cells of secondary lymphoid organs, liver hepatocytes, lung bronchial and alveolar epithelial cells, lung vascular smooth muscle, endothelial cells astrocytes, microglia, and fibroblast-like cells of the brain. The C85-2506 is a rabbit monoclonal antibody generated by fusion of splenocytes from rabbits immunized with human C5aR peptides and the rabbit fusion partner 240E-1. C85-2506 staining on dendritic cells and granulocytes of human tonsil paraffin sections.

    BD Pharmingen™ Purified Rabbit Anti-Human CD88 - Purified - Clone C85-2506 - Isotype Rabbit IgG - Reactivity Hu - 1 mL
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    C85
    亚型
    IgG
    Top Product
    Discover our top product C5AR1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Fayyazi, Sandau, Duong, Götze, Radzun, Schweyer, Soruri, Zwirner: "C5a receptor and interleukin-6 are expressed in tissue macrophages and stimulated keratinocytes but not in pulmonary and intestinal epithelial cells." in: The American journal of pathology, Vol. 154, Issue 2, pp. 495-501, (1999) (PubMed).

    Paradisis, Campbell, Barnum: "Elevated complement C5a receptor expression on neurons and glia in astrocyte-targeted interleukin-3 transgenic mice." in: Glia, Vol. 24, Issue 3, pp. 338-45, (1999) (PubMed).

    Nataf, Davoust, Barnum: "Kinetics of anaphylatoxin C5a receptor expression during experimental allergic encephalomyelitis." in: Journal of neuroimmunology, Vol. 91, Issue 1-2, pp. 147-55, (1998) (PubMed).

    Stahel, Frei, Eugster, Fontana, Hummel, Wetsel, Ames, Barnum: "TNF-alpha-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 2, pp. 861-9, (1997) (PubMed).

    Morelli, Larregina, Chuluyán, Kolkowski, Fainboim: "Expression and modulation of C5a receptor (CD88) on skin dendritic cells. Chemotactic effect of C5a on skin migratory dendritic cells." in: Immunology, Vol. 89, Issue 1, pp. 126-34, (1996) (PubMed).

    Füreder, Agis, Willheim, Bankl, Maier, Kishi, Müller, Czerwenka, Radaszkiewicz, Butterfield, Klappacher, Sperr, Oppermann, Lechner, Valent: "Differential expression of complement receptors on human basophils and mast cells. Evidence for mast cell heterogeneity and CD88/C5aR expression on skin mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 6, pp. 3152-60, (1995) (PubMed).

    Haviland, McCoy, Whitehead, Akama, Molmenti, Brown, Haviland, Parks, Perlmutter, Wetsel: "Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 4, pp. 1861-9, (1995) (PubMed).

    Spieker-Polet, Sethupathi, Yam, Knight: "Rabbit monoclonal antibodies: generating a fusion partner to produce rabbit-rabbit hybridomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 20, pp. 9348-52, (1995) (PubMed).

    Wetsel: "Expression of the complement C5a anaphylatoxin receptor (C5aR) on non-myeloid cells." in: Immunology letters, Vol. 44, Issue 2-3, pp. 183-7, (1995) (PubMed).

  • 抗原
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    别名
    CD88 (C5AR1 产品)
    别名
    C5A antibody, C5AR antibody, C5R1 antibody, CD88 antibody, C5aR antibody, C5r1 antibody, Cd88 antibody, D7Msu1 antibody, GPR77 antibody, complement C5a receptor 1 antibody, complement component 5a receptor 1 antibody, C5AR1 antibody, C5ar1 antibody, c5ar1 antibody
    背景
    Synonyms: C5a Receptor
    途径
    Complement System
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