CD81 抗体
Quick Overview for CD81 抗体 (ABIN2689415)
抗原
See all CD81 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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JS-81 identifies the newly clustered CD81 antigen, a 26 kDa, type III transmembrane protein (also known as TAPA-1) that is involved in cell growth and signal transduction. CD81 has a very broad cellular distribution, being expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin. MAbs to CD81 have been shown to have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. Immunoprecipitation studies reveal that CD81 is a component of a multimolecular complex which can include the Leu13 Molecule, and the CD19 and CD21 Molecules in B cells. MAbs to CD81 are reported to induce homotypic cell aggregation. Profile of peripheral blood lymphocytes analyzed on a FACScan
BD Pharmingen™ Purified Mouse Anti-Human CD81 - Purified - Clone JS-81 - Isotype Mouse IgG1, κ - Reactivity Hu, Dog, Rab - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "The TAPA-1 molecule is associated on the surface of B cells with HLA-DR molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 8, pp. 4090-7, (1993) (PubMed).
: "TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins." in: Molecular and cellular biology, Vol. 10, Issue 8, pp. 4007-15, (1990) (PubMed).
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: "The TAPA-1 molecule is associated on the surface of B cells with HLA-DR molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 8, pp. 4090-7, (1993) (PubMed).
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- CD81
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别名
- CD81
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背景
- Synonyms: TAPA-1
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途径
- Inositol Metabolic Process, Hepatitis C
抗原
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