CEACAM1 抗体
Quick Overview for CEACAM1 抗体 (ABIN2689373)
抗原
See all CEACAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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Reacts with several glycosylphosphatidylinositol-anchored glycoproteins present on granulocytes and epithelial cells. Antibody B1.1 was studied as recognizing CD66a, c, d and e in the VI Human Leukocyte Differentiation Workshop. CD66 antigens, also known as the carcinoembryonic antigen (CEA) family of molecules, are closely related to the immunoglobulin superfamily of glycoproteins. Studies on CD66 Molecules suggest a potential adhesion function in vivo. These molecules exhibit both homophilic and heterophilic ashesion. CEA family members may be involved in transmembrane signalling and activation of neutrophils. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood granulocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.
BD Pharmingen™ Purified Mouse Anti-Human CD66 - Purified - Clone B1.1/CD66 - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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亚型
- IgG2a kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Genomic organization, splice variants and expression of CGM1, a CD66-related member of the carcinoembryonic antigen gene family." in: European journal of biochemistry / FEBS, Vol. 214, Issue 1, pp. 27-35, (1993) (PubMed).
: "Molecular cloning of nonspecific cross-reacting antigens in human granulocytes." in: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 11810-7, (1991) (PubMed).
: "Carcinoembryonic antigen gene family: molecular biology and clinical perspectives." in: Journal of clinical laboratory analysis, Vol. 5, Issue 5, pp. 344-66, (1991) (PubMed).
: "Patterns of reactivity of four novel monoclonal antibodies (B72.3, DF3, B1.1 and B6.2) with cells in human malignant and benign effusions." in: Acta cytologica, Vol. 28, Issue 4, pp. 356-67, (1984) (PubMed).
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: "Genomic organization, splice variants and expression of CGM1, a CD66-related member of the carcinoembryonic antigen gene family." in: European journal of biochemistry / FEBS, Vol. 214, Issue 1, pp. 27-35, (1993) (PubMed).
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- CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))
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别名
- CD66
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背景
- Synonyms: CEA, carcinoembryonic antigen
抗原
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