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CD6 抗体

CD6 适用: 大鼠 FACS, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal OX unconjugated
产品编号 ABIN2689349
发货至: 中国
  • 抗原 See all CD6 抗体
    CD6
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    大鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD6 antibody is un-conjugated
    应用范围
    • 55
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    品牌
    BD Pharmingen™
    产品特性
    The OX-52 antibody reacts with CD6, a 95-120- kDa antigen on T lymphocytes and thymocytes expressing αβ and γδ Tcell receptors. Rat NK cells express low levels of CD6 and are CD8a+, CD8b-, CD5-, and CD3-. In immunoprecipitation experiments, CD6 has been shown to co-precipitate with CD5 and to play a key role in CD5 tyrosine phosphorylation. Two-color evaluation of splenic T lymphocytes. LEW splenocytes were simultaneously stained with PE-conjugated anti-rat CD3 mAb G4.18 (Cat. No. 554833) and purified mAb OX-52 (right panel), followed by FITC-conjugated anti-mouse IgG2a mAb R19-15 (Cat. No. 553390). Flow cytometry was performed on a BD FACScan™ flow cytometry system.

    BD Pharmingen™ Purified Mouse Anti-Rat CD6 - Purified - Clone OX-52 - Isotype Mouse IgG2a, κ - Reactivity Rat - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    PVG-RT1c rat thoracic-duct leukocytes and splenocytes
    克隆位点
    OX
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Castro, Nunes, Oliveira, Tavares, Simões, Parnes, Moreira, Carmo: "OX52 is the rat homologue of CD6: evidence for an effector function in the regulation of CD5 phosphorylation." in: Journal of leukocyte biology, Vol. 73, Issue 1, pp. 183-90, (2003) (PubMed).

    Lawetzky, Tiefenthaler, Kubo, Hünig: "Identification and characterization of rat T cell subpopulations expressing T cell receptors alpha/beta and gamma/delta." in: European journal of immunology, Vol. 20, Issue 2, pp. 343-9, (1990) (PubMed).

    Robinson, Puklavec, Mason: "MRC OX-52: a rat T-cell antigen." in: Immunology, Vol. 57, Issue 4, pp. 527-31, (1986) (PubMed).

  • 抗原
    CD6
    别名
    CD6 (CD6 产品)
    别名
    TP120 antibody, OX52 antibody, CD6 antigen antibody, CD6 molecule antibody, Cd6 molecule antibody, Cd6 antibody, CD6 antibody
    背景
    Synonyms: OX-52 Antigen, Pan-T Cells
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