电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CD6 抗体

This 小鼠 单克隆 antibody specifically detects CD6 in FACS, IP, IHC (p) 和 IHC (fro). It exhibits reactivity toward 大鼠. It has been mentioned in 3+ publications
产品编号 ABIN2689349
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD6 抗体 (ABIN2689349)

抗原

See all CD6 抗体
CD6

适用

  • 131
  • 40
  • 20
  • 1
  • 1
  • 1
  • 1
大鼠

宿主

  • 70
  • 61
  • 8
  • 5
小鼠

克隆类型

  • 93
  • 45
  • 4
单克隆

标记

  • 55
  • 11
  • 10
  • 8
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD6 antibody is un-conjugated

应用范围

  • 84
  • 57
  • 54
  • 31
  • 19
  • 18
  • 13
  • 12
  • 10
  • 6
  • 6
  • 2
  • 2
  • 2
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

OX
  • 产品特性

    The OX-52 antibody reacts with CD6, a 95-120- kDa antigen on T lymphocytes and thymocytes expressing αβ and γδ Tcell receptors. Rat NK cells express low levels of CD6 and are CD8a+, CD8b-, CD5-, and CD3-. In immunoprecipitation experiments, CD6 has been shown to co-precipitate with CD5 and to play a key role in CD5 tyrosine phosphorylation. Two-color evaluation of splenic T lymphocytes. LEW splenocytes were simultaneously stained with PE-conjugated anti-rat CD3 mAb G4.18 (Cat. No. 554833) and purified mAb OX-52 (right panel), followed by FITC-conjugated anti-mouse IgG2a mAb R19-15 (Cat. No. 553390). Flow cytometry was performed on a BD FACScan™ flow cytometry system.

    BD Pharmingen™ Purified Mouse Anti-Rat CD6 - Purified - Clone OX-52 - Isotype Mouse IgG2a, κ - Reactivity Rat - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    PVG-RT1c rat thoracic-duct leukocytes and splenocytes

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Castro, Nunes, Oliveira, Tavares, Simões, Parnes, Moreira, Carmo: "OX52 is the rat homologue of CD6: evidence for an effector function in the regulation of CD5 phosphorylation." in: Journal of leukocyte biology, Vol. 73, Issue 1, pp. 183-90, (2003) (PubMed).

    Lawetzky, Tiefenthaler, Kubo, Hünig: "Identification and characterization of rat T cell subpopulations expressing T cell receptors alpha/beta and gamma/delta." in: European journal of immunology, Vol. 20, Issue 2, pp. 343-9, (1990) (PubMed).

    Robinson, Puklavec, Mason: "MRC OX-52: a rat T-cell antigen." in: Immunology, Vol. 57, Issue 4, pp. 527-31, (1986) (PubMed).

  • 抗原

    CD6

    别名

    CD6

    背景

    Synonyms: OX-52 Antigen, Pan-T Cells
You are here: