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CD55 抗体

This 小鼠 单克隆 antibody specifically detects CD55 in FACS 和 IHC (fro). It exhibits reactivity toward 人.It has been mentioned in 1 publication
产品编号 ABIN2689337
发货至: 中国
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Quick Overview for CD55 抗体 (ABIN2689337)

抗原

See all CD55 抗体
CD55 (Complement Decay-Accelerating Factor (CD55))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD55 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

IA10
  • 产品特性

    Reacts with CD55, decay-accelerating factor (DAF), a glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein of approximately 70 kDa, expressed on hematopoietic cells. It has been suggested that the role of DAF is to protect cells from damage by autologous complement preventing the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertases, C4b2a3b and C3bBb3b. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of K562 cells expressing glycosylphosphatidylinositol (GPI) anchor protein analyzed by flow cytometry Profile of glycosylphosphatidylinositol (GPI) anchor-defective mutant cell line analyzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD55 - Purified - Clone IA10 - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Loveland, Szokolai, Johnstone, McKenzie: "Coordinate functions of multiple complement regulating molecules, CD46, CD55, and CD59." in: Transplantation proceedings, Vol. 26, Issue 3, pp. 1070-1, (1994) (PubMed).

  • 抗原

    CD55 (Complement Decay-Accelerating Factor (CD55))

    别名

    CD55

    背景

    Synonyms: DAF

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity
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