ICAM1 抗体
Quick Overview for ICAM1 抗体 (ABIN2689333)
抗原
See all ICAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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Anti-ICAM-1 (CD54) monoclonal antibody (clone LB-2) recognizes an inducible 76- to 110 kD glycoprotein, intercellular adhesion molecule-1 (ICAM-1), the CD54 antigen, that is expressed on human myeloma cells, Burkitt's lymphoma cells, erythroleukemia cells, B-lymphoblastoid cells, monocytes, and granulocytes, but not on T-cell lines, resting T lymphocytes or T-cell leukemias.
BD Pharmingen™ Purified Mouse Anti-Human CD54 - Purified - Clone LB-2 - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.2 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Major histocompatibility Class II antigen negative variant of human B-lymphoblastoid cell line
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亚型
- IgG2b kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Endothelial-leukocyte adhesion molecule 1 stimulates the adhesive activity of leukocyte integrin CR3 (CD11b/CD18, Mac-1, alpha m beta 2) on human neutrophils." in: The Journal of experimental medicine, Vol. 173, Issue 6, pp. 1493-500, (1991) (PubMed).
: "ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18)." in: The Journal of cell biology, Vol. 111, Issue 6 Pt 2, pp. 3129-39, (1991) (PubMed).
: "ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex." in: Science (New York, N.Y.), Vol. 250, Issue 4984, pp. 1130-2, (1991) (PubMed).
: "Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins." in: Science (New York, N.Y.), Vol. 243, Issue 4895, pp. 1160-5, (1989) (PubMed).
: "Identification of an inducible endothelial-leukocyte adhesion molecule." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 24, pp. 9238-42, (1988) (PubMed).
: "ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells." in: Nature, Vol. 331, Issue 6151, pp. 86-8, (1988) (PubMed).
: "Identification of a novel adhesion molecule in human leukocytes by monoclonal antibody LB-2." in: FEBS letters, Vol. 210, Issue 2, pp. 127-31, (1987) (PubMed).
: "Polypeptides on human B lymphocytes associated with cell activation." in: Human immunology, Vol. 16, Issue 1, pp. 100-13, (1986) (PubMed).
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: "Endothelial-leukocyte adhesion molecule 1 stimulates the adhesive activity of leukocyte integrin CR3 (CD11b/CD18, Mac-1, alpha m beta 2) on human neutrophils." in: The Journal of experimental medicine, Vol. 173, Issue 6, pp. 1493-500, (1991) (PubMed).
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- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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别名
- CD54
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背景
- Synonyms: Human ICAM-1, HICAM-1
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
抗原
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