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ICAM1 抗体

Cited in 8+ publications. This 小鼠 单克隆 anti-ICAM1 antibody (Clone LB) specifically detects ICAM1 in FACS, IHC, IP 和 Func. The antibody is reactive with 人 samples.
产品编号 ABIN2689333
发货至: 中国
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Quick Overview for ICAM1 抗体 (ABIN2689333)

抗原

See all ICAM1 抗体
ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

适用

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小鼠

克隆类型

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单克隆

标记

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This ICAM1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func)

克隆位点

LB
  • 产品特性

    Anti-ICAM-1 (CD54) monoclonal antibody (clone LB-2) recognizes an inducible 76- to 110 kD glycoprotein, intercellular adhesion molecule-1 (ICAM-1), the CD54 antigen, that is expressed on human myeloma cells, Burkitt's lymphoma cells, erythroleukemia cells, B-lymphoblastoid cells, monocytes, and granulocytes, but not on T-cell lines, resting T lymphocytes or T-cell leukemias.

    BD Pharmingen™ Purified Mouse Anti-Human CD54 - Purified - Clone LB-2 - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.2 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Major histocompatibility Class II antigen negative variant of human B-lymphoblastoid cell line

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Lo, Lee, Ramos, Lobb, Rosa, Chi-Rosso, Wright: "Endothelial-leukocyte adhesion molecule 1 stimulates the adhesive activity of leukocyte integrin CR3 (CD11b/CD18, Mac-1, alpha m beta 2) on human neutrophils." in: The Journal of experimental medicine, Vol. 173, Issue 6, pp. 1493-500, (1991) (PubMed).

    Diamond, Staunton, de Fougerolles, Stacker, Garcia-Aguilar, Hibbs, Springer: "ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18)." in: The Journal of cell biology, Vol. 111, Issue 6 Pt 2, pp. 3129-39, (1991) (PubMed).

    Phillips, Nudelman, Gaeta, Perez, Singhal, Hakomori, Paulson: "ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex." in: Science (New York, N.Y.), Vol. 250, Issue 4984, pp. 1130-2, (1991) (PubMed).

    Bevilacqua, Stengelin, Gimbrone, Seed: "Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins." in: Science (New York, N.Y.), Vol. 243, Issue 4895, pp. 1160-5, (1989) (PubMed).

    Bevilacqua, Pober, Mendrick, Cotran, Gimbrone: "Identification of an inducible endothelial-leukocyte adhesion molecule." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 24, pp. 9238-42, (1988) (PubMed).

    Makgoba, Sanders, Ginther Luce, Dustin, Springer, Clark, Mannoni, Shaw: "ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells." in: Nature, Vol. 331, Issue 6151, pp. 86-8, (1988) (PubMed).

    Patarroyo, Clark, Prieto, Kantor, Gahmberg: "Identification of a novel adhesion molecule in human leukocytes by monoclonal antibody LB-2." in: FEBS letters, Vol. 210, Issue 2, pp. 127-31, (1987) (PubMed).

    Clark, Ledbetter, Holly, Dinndorf, Shu: "Polypeptides on human B lymphocytes associated with cell activation." in: Human immunology, Vol. 16, Issue 1, pp. 100-13, (1986) (PubMed).

  • 抗原

    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

    别名

    CD54

    背景

    Synonyms: Human ICAM-1, HICAM-1

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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