CD44 Standard 抗体
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北京 101111
Quick Overview for CD44 Standard 抗体 (ABIN2689266)
抗原
See all CD44 Standard (CD44s) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
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The OX-49 antibody reacts with the glycoprotein CD44H (also known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes, and at greatly increased levels on T- and B-cell blasts. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However, recent reports indicate that OX-49 antibody cannot detect the CD44v isoform, possibly due to conformational changes in the epitope. CD44 is a cell adhesion receptor, and its ligand, hyaluronate, is a common component of extracellular matrices.
BD Pharmingen™ Purified Mouse Anti-Rat CD44H - Purified - Clone OX-49 - Isotype Mouse IgG2a, κ - Reactivity Rat - 0.5 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Rat T blasts from mixed lymphocyte reactions
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亚型
- IgG2a kappa
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anti-CD44 Standard (CD44s) antibody
CD44s 适用: 人, Non-Human Primate FACS, IF, IHC (f) 宿主: 小鼠 Monoclonal HCAM-918 unconjugated
anti-CD44 Standard (CD44s) antibodyCD44s 适用: 人, Baboon, Green Monkey FACS, IF, IHC (f), WB 宿主: 小鼠 Monoclonal 156-3C11 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Spatial distribution of CD44 and hyaluronan in the proximal tibia of the growing rat." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 14, Issue 4, pp. 573-81, (1996) (PubMed).
: "CD44 in growing normal and neoplastic rat cartilage." in: Annals of the New York Academy of Sciences, Vol. 785, pp. 333-6, (1996) (PubMed).
: "Monoclonal antibodies to CD44 and their influence on hyaluronan recognition." in: The Journal of cell biology, Vol. 130, Issue 2, pp. 485-95, (1995) (PubMed).
: "B and T lymphocyte subsets enter peripheral lymph nodes and Peyer's patches without preference in vivo: no correlation occurs between their localization in different types of high endothelial venules ..." in: European journal of immunology, Vol. 24, Issue 10, pp. 2312-6, (1994) (PubMed).
: "CD44 and its interaction with extracellular matrix." in: Advances in immunology, Vol. 54, Issue 4, pp. 271-335, (1993) (PubMed).
: "Participation in normal immune responses of a metastasis-inducing splice variant of CD44." in: Science (New York, N.Y.), Vol. 257, Issue 5070, pp. 682-5, (1992) (PubMed).
: "Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts." in: Molecular immunology, Vol. 24, Issue 12, pp. 1281-90, (1988) (PubMed).
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: "Spatial distribution of CD44 and hyaluronan in the proximal tibia of the growing rat." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 14, Issue 4, pp. 573-81, (1996) (PubMed).
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- CD44 Standard (CD44s)
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别名
- CD44H
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背景
- Synonyms: Pgp-1, H-CAM, CD44s
抗原
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