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CD4 抗体

This 小鼠 单克隆 antibody specifically detects CD4 in FACS. It exhibits reactivity toward 猕猴, Cynomolgus 和 Baboon. It has been mentioned in 4+ publications
产品编号 ABIN2689220
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD4 抗体 (ABIN2689220)

抗原

See all CD4 抗体
CD4

适用

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猕猴, Cynomolgus, Baboon

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

L200
  • 产品特性

    The L200 antibody reacts with the human form of the 56 kDa transmembrane glycoprotein, CD4, present on the T-helper/inducer subset of normal human donor peripheral blood lymphocytes. L200 antibody also cross-reacts with a subset of CD3-positive peripheral blood lymphocytes, but not monocytes, of both rhesus and cynomolgus macaque monkeys. Cross-reactivity on both lymphocytes and monocytes (weak) of baboon is also observed. The distribution on lymphocytes is similar for both human and monkey, with the majority of CD4-positive lymphocytes being CD8-negative and lacking reactivity with antibodies to B- or NK-cell markers. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of anti-CD4 reactivity on peripheral blood lymphocytes of rhesus macaque (Macaca mulatta) analyzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD4 - Purified - Clone L200 - Isotype Mouse IgG1, κ - Reactivity Bab, Cyno, Rhe - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Verdier, Aujoulat, Condevaux, Descotes: "Determination of lymphocyte subsets and cytokine levels in cynomolgus monkeys." in: Toxicology, Vol. 105, Issue 1, pp. 81-90, (1996) (PubMed).

    Jacobsen, Aasted, Broe, Petersen: "Reactivities of 20 anti-human monoclonal antibodies with leucocytes from ten different animal species." in: Veterinary immunology and immunopathology, Vol. 39, Issue 4, pp. 461-6, (1994) (PubMed).

    Indzhiia, Yakovleva, Overbaugh, Licciardi, Chikobava, Klotz, Torres, Indzhiia, Lapin, Clark: "Baboon T cell lymphomas expressing the B cell-associated surface proteins CD40 and Bgp95." in: Journal of clinical immunology, Vol. 12, Issue 3, pp. 225-36, (1992) (PubMed).

    Powell, McClure, Anderson, Fultz, Sell, Ahmed-Ansari: "Phenotypic and functional differences in NK and LAK cells in the peripheral blood of sooty mangabeys and rhesus macaques." in: Cellular immunology, Vol. 124, Issue 1, pp. 107-18, (1989) (PubMed).

  • 抗原

    CD4

    别名

    CD4

    途径

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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