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Cadherin 5 抗体

Cited in 3+ publications. The 大鼠 单克隆 anti-Cadherin 5 antibody (Clone 11D4-1) (ABIN2688979) specifically detects Cadherin 5 in FACS, IHC (fro) 和 IHC (f). The antibody is reactive with 小鼠 samples.
产品编号 ABIN2688979
发货至: 中国
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Quick Overview for Cadherin 5 抗体 (ABIN2688979)

抗原

See all Cadherin 5 (CDH5) 抗体
Cadherin 5 (CDH5)

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Cadherin 5 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

11D4-1
  • 产品特性

    The 11D4.1 antibody reacts with mouse VE-cadherin, a member of the cadherin family. VE-cadherin is an endothelial cell-specific, homophilic adhesion molecule. It is concentrated at interendothelial cells contacts and is thought to be involved in the maintenance of cell layer integrity. In vitro and in vivo studies indicate that the 11D.4 mAb interferes with VE-cadherin-mediated intercellular adhesion. Immunohistochemical staining of CD144. Frozen sections of normal mouse small intestine were reacted with the anti-CD144 antibody. Cells expressing VE-Cadherin can be identified by the brown labeling of their cell membranes. Amplification 20X.

    BD Pharmingen™ Purified Rat Anti-Mouse CD144 - Purified - Clone 11D4.1 - Isotype Rat IgG2a, κ - Reactivity Ms - 1 mL

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Mouse VE-Cadherin-Ig Fusion

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    125 μg/mL

    缓冲液

    Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Gotsch, Borges, Bosse, Böggemeyer, Simon, Mossmann, Vestweber: "VE-cadherin antibody accelerates neutrophil recruitment in vivo." in: Journal of cell science, Vol. 110 ( Pt 5), pp. 583-8, (1997) (PubMed).

    Breier, Breviario, Caveda, Berthier, Schnürch, Gotsch, Vestweber, Risau, Dejana: "Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system." in: Blood, Vol. 87, Issue 2, pp. 630-41, (1996) (PubMed).

    Lampugnani, Resnati, Raiteri, Pigott, Pisacane, Houen, Ruco, Dejana: "A novel endothelial-specific membrane protein is a marker of cell-cell contacts." in: The Journal of cell biology, Vol. 118, Issue 6, pp. 1511-22, (1992) (PubMed).

  • 抗原

    Cadherin 5 (CDH5)

    别名

    CD144

    背景

    Synonyms: VE-Cadherin, Cadherin-5

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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