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Cadherin 5 抗体

CDH5 适用: 小鼠 FACS, IP, IHC (fro), BR 宿主: 大鼠 Monoclonal 11D4-1 unconjugated
产品编号 ABIN2688978
发货至: 中国
  • 抗原 See all Cadherin 5 (CDH5) 抗体
    Cadherin 5 (CDH5)
    适用
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    小鼠
    宿主
    • 88
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    大鼠
    克隆类型
    • 85
    • 30
    单克隆
    标记
    • 68
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    This Cadherin 5 antibody is un-conjugated
    应用范围
    • 84
    • 36
    • 35
    • 33
    • 17
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    • 9
    • 5
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)
    品牌
    BD Pharmingen™
    产品特性
    The 11D4.1 antibody reacts with mouse VE-cadherin, a member of the cadherin family. VE-cadherin is an endothelial cell-specific, homophilic adhesion molecule. It is concentrated at interendothelial cells contacts and is thought to be involved in the maintenance of cell layer integrity. In vitro and in vivo studies indicate that the 11D.4 mAb interferes with VE-cadherin-mediated intercellular adhesion. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

    BD Pharmingen™ Purified Rat Anti-Mouse CD144 - Purified - Clone 11D4.1 - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Mouse VE-Cadherin-Ig Fusion Protein
    克隆位点
    11D4-1
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CDH5 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Gotsch, Borges, Bosse, Böggemeyer, Simon, Mossmann, Vestweber: "VE-cadherin antibody accelerates neutrophil recruitment in vivo." in: Journal of cell science, Vol. 110 ( Pt 5), pp. 583-8, (1997) (PubMed).

    Breier, Breviario, Caveda, Berthier, Schnürch, Gotsch, Vestweber, Risau, Dejana: "Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system." in: Blood, Vol. 87, Issue 2, pp. 630-41, (1996) (PubMed).

    Lampugnani, Resnati, Raiteri, Pigott, Pisacane, Houen, Ruco, Dejana: "A novel endothelial-specific membrane protein is a marker of cell-cell contacts." in: The Journal of cell biology, Vol. 118, Issue 6, pp. 1511-22, (1992) (PubMed).

  • 抗原
    Cadherin 5 (CDH5)
    别名
    CD144 (CDH5 产品)
    别名
    7B4 antibody, AA408225 antibody, Cd144 antibody, VE-Cad antibody, VECD antibody, VEcad antibody, Vec antibody, wu:fc88a07 antibody, CD144 antibody, cadherin-5 antibody, cadherin 5 antibody, CDH5 antibody, Cdh5 antibody, cdh5 antibody
    背景
    Synonyms: VE-Cadherin, Cadherin-5
    途径
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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