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IL2 Receptor beta 抗体

IL2RB 适用: 小鼠 FACS, IP 宿主: 大鼠 Monoclonal 5H4 unconjugated
产品编号 ABIN2688930
发货至: 中国
  • 抗原 See all IL2 Receptor beta (IL2RB) 抗体
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    适用
    • 91
    • 74
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    小鼠
    宿主
    • 85
    • 22
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    大鼠
    克隆类型
    • 86
    • 40
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    单克隆
    标记
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    This IL2 Receptor beta antibody is un-conjugated
    应用范围
    • 73
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    品牌
    BD Pharmingen™
    产品特性
    The 5H4 antibody reacts with mouse CD122, the 75-85kD β chain of the mouse IL-2 receptor, but does not block IL-2 binding to the IL-2 receptor. The IL-2R β chain is constitutively expressed on a subset of CD8+ spleen T cells, on NK cells, and at lower levels on a small population of resting B cells. IL-2R β chain expression is up-regulated by IL-2. The immunogen used to generate this hybridoma was rat myeloma cells transfected with a truncated IL-2R β cDNA.

    BD Pharmingen™ Purified Rat Anti-Mouse CD122 - Purified - Clone 5H4 - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Rat myeloma cells transfected with a truncated IL-2R beta cDNA
    克隆位点
    5H4
    亚型
    IgG2a kappa
    Top Product
    Discover our top product IL2RB Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Malek, Furse, Fleming, Fadell, He: "Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 15, Issue 5, pp. 447-54, (1995) (PubMed).

    Furse, Malek et al.: "Selection of internalization-deficient cells by interleukin-2-Pseudomonas exotoxin chimeric protein: the cytoplasmic domain of the interleukin-2 receptor beta chain does not contribute to ..." in: European journal of immunology, Vol. 23, Issue 12, pp. 3181-8, (1994) (PubMed).

  • 抗原
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    别名
    CD122 (IL2RB 产品)
    别名
    IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
    背景
    Synonyms: IL-2 and IL-15 Receptor β chain, P75
    途径
    JAK/STAT Signaling, Growth Factor Binding
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