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IL2 Receptor beta 抗体

There are 2+ publications for this product available. The 大鼠 单克隆 anti-IL2 Receptor beta antibody is suitable to detect IL2 Receptor beta in samples from 小鼠. It has been validated for FACS 和 IP.
产品编号 ABIN2688930
发货至: 中国
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Quick Overview for IL2 Receptor beta 抗体 (ABIN2688930)

抗原

See all IL2 Receptor beta (IL2RB) 抗体
IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This IL2 Receptor beta antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

5H4
  • 产品特性

    The 5H4 antibody reacts with mouse CD122, the 75-85kD β chain of the mouse IL-2 receptor, but does not block IL-2 binding to the IL-2 receptor. The IL-2R β chain is constitutively expressed on a subset of CD8+ spleen T cells, on NK cells, and at lower levels on a small population of resting B cells. IL-2R β chain expression is up-regulated by IL-2. The immunogen used to generate this hybridoma was rat myeloma cells transfected with a truncated IL-2R β cDNA.

    BD Pharmingen™ Purified Rat Anti-Mouse CD122 - Purified - Clone 5H4 - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Rat myeloma cells transfected with a truncated IL-2R beta cDNA

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Malek, Furse, Fleming, Fadell, He: "Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 15, Issue 5, pp. 447-54, (1995) (PubMed).

    Furse, Malek et al.: "Selection of internalization-deficient cells by interleukin-2-Pseudomonas exotoxin chimeric protein: the cytoplasmic domain of the interleukin-2 receptor beta chain does not contribute to ..." in: European journal of immunology, Vol. 23, Issue 12, pp. 3181-8, (1994) (PubMed).

  • 抗原

    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

    别名

    CD122

    背景

    Synonyms: IL-2 and IL-15 Receptor β chain, P75

    途径

    JAK/STAT Signaling, Growth Factor Binding
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