IL2 Receptor beta 抗体
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Quick Overview for IL2 Receptor beta 抗体 (ABIN2688930)
抗原
See all IL2 Receptor beta (IL2RB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
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The 5H4 antibody reacts with mouse CD122, the 75-85kD β chain of the mouse IL-2 receptor, but does not block IL-2 binding to the IL-2 receptor. The IL-2R β chain is constitutively expressed on a subset of CD8+ spleen T cells, on NK cells, and at lower levels on a small population of resting B cells. IL-2R β chain expression is up-regulated by IL-2. The immunogen used to generate this hybridoma was rat myeloma cells transfected with a truncated IL-2R β cDNA.
BD Pharmingen™ Purified Rat Anti-Mouse CD122 - Purified - Clone 5H4 - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Rat myeloma cells transfected with a truncated IL-2R beta cDNA
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亚型
- IgG2a kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 15, Issue 5, pp. 447-54, (1995) (PubMed).
: "Selection of internalization-deficient cells by interleukin-2-Pseudomonas exotoxin chimeric protein: the cytoplasmic domain of the interleukin-2 receptor beta chain does not contribute to ..." in: European journal of immunology, Vol. 23, Issue 12, pp. 3181-8, (1994) (PubMed).
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: "Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 15, Issue 5, pp. 447-54, (1995) (PubMed).
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- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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别名
- CD122
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背景
- Synonyms: IL-2 and IL-15 Receptor β chain, P75
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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