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C3a 抗体

This anti-C3a antibody is a 大鼠 单克隆 antibody detecting C3a in ELISA. Suitable for 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2688860
发货至: 中国

Quick Overview for C3a 抗体 (ABIN2688860)

抗原

See all C3a 抗体
C3a (Complement Fragment 3a (C3a))

适用

  • 33
  • 10
  • 4
  • 2
  • 1
  • 1
小鼠

宿主

  • 31
  • 13
  • 4
  • 1
大鼠

克隆类型

  • 32
  • 16
  • 1
单克隆

标记

  • 44
  • 3
  • 1
  • 1
This C3a antibody is un-conjugated

应用范围

  • 44
  • 30
  • 30
  • 30
  • 8
  • 2
  • 2
  • 1
  • 1
ELISA

克隆位点

I87
  • 品牌

    BD Pharmingen™

    产品特性

    The purified I87-1162 antibody reacts with the mouse C3a protein. The I87-1162 antibody is specific for a neoepitope exposed in mouse C3a/C3adesArg and does not cross-react with mouse C3. This capacity makes antibody I87-1162 a preferential capture antibody for direct detection of mouse C3a from plasma or serum samples in an ELISA sandwich assay. Anaphylatoxin C3a is a bioactive cleavage product released from plasma component C3 during complement activation and is involved in mediation of a variety of cellular immune responses, as well as being a potent pro-inflammatory agent. The release of this cleavage product is a reliable indicator of in vivo or in vitro complement activation. Representative Mouse C3a standard curve. The curve was generated by a sandwich ELISA using the purified I87-1162 antibody (Cat. No. 558250) as capture antibody, doubling dilutions of purified mouse C3a protein (Cat. No. 558618) as standard, and biotinylated I87-419 antibody (Cat. No. 558251) as detection antibody. The standard curve is displayed as the concentration of purified mouse C3a in ng/mL versus the microwell absorbance.

    BD Pharmingen™ Purified Rat Anti-Mouse C3a - Purified - Clone I87-1162 - Isotype Rat IgG1, κ - Reactivity Ms - 0.1 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    ELISA) Hugli T.E. Structure and function of the anaphylatoxins.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • Hugli: "Structure and function of C3a anaphylatoxin." in: Current topics in microbiology and immunology, Vol. 153, pp. 181-208, (1990) (PubMed).

    Hugli: "Structure and function of the anaphylatoxins." in: Springer seminars in immunopathology, Vol. 7, Issue 2-3, pp. 193-219, (1984) (PubMed).

  • 抗原

    C3a (Complement Fragment 3a (C3a))

    别名

    C3a

    途径

    Complement System
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