TIE1 抗体 (AA 385-607)
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Quick Overview for TIE1 抗体 (AA 385-607) (ABIN2683015)
抗原
See all TIE1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 385-607
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原理
- TIE1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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别名
- TIE1
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背景
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This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 125 kDa
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UniProt
- P35590
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途径
- RTK signaling
抗原
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