BACE1 抗体 (AA 112-324)
Quick Overview for BACE1 抗体 (AA 112-324) (ABIN2682977)
抗原
See all BACE1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 112-324
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原理
- BACE1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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别名
- BACE1
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背景
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Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
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分子量
- 55.7 kDa
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基因ID
- 23621
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UniProt
- P56817
抗原
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