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ZBTB16 抗体

There are 3+ publications for this product available. The 小鼠 单克隆 anti-ZBTB16 antibody is suitable to detect ZBTB16 in samples from 人 和 小鼠. It has been validated for WB, IF, ICC, IP 和 ChIP.
产品编号 ABIN2668927
发货至: 中国
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Quick Overview for ZBTB16 抗体 (ABIN2668927)

抗原

See all ZBTB16 抗体
ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

适用

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人, 小鼠

宿主

  • 61
  • 10
小鼠

克隆类型

  • 60
  • 11
单克隆

标记

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This ZBTB16 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

克隆位点

2A9
  • 原理

    PLZF antibody (mAb) (Clone 2A9)

    纯化方法

    Protein G Chromatography

    免疫原

    This PLZF antibody was raised against a recombinant protein corresponding to full-length mouse PLZF with a GST-Tag.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    PBS pH 7.5 containing 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Felli, Errico, Pedini, Petrini, Puglisi, Bellenghi, Boe, Felicetti, Mattia, De Feo, Bottero, Tripodo, Carè: "AP2α controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression." in: Oncogene, Vol. 35, Issue 23, pp. 3016-26, (2016) (PubMed).

    Chapman, Medrano, Chaudhary, Hamra: "NRG1 and KITL Signal Downstream of Retinoic Acid in the Germline to Support Soma-Free Syncytial Growth of Differentiating Spermatogonia." in: Cell death discovery, Vol. 1, (2015) (PubMed).

    Koken, Reid, Quignon, Chelbi-Alix, Davies, Kabarowski, Zhu, Dong, Chen, Chen, Tan, Licht, Waxman, de Thé, Zelent: "Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 19, pp. 10255-60, (1997) (PubMed).

  • 抗原

    ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

    别名

    PLZF

    背景

    PLZF (Promyelocytic Leukemia Zinc-Finger protein) is a member of the POK (POZ and Krüppel) family of transcriptional repressors. PLZF is expressed in early, but not differentiated, hematopoietic cells, and is required for spermatogonial stem cell maintenance. In addition, PLZF regulates genes involved in cellular proliferation and differentiation (cyclin A2, Myc and Hox genes) and targeted deletion of PLZF in mice results in limb and axial skeleton and limb deformations.

    分子量

    90 kDa

    基因ID

    235320

    NCBI登录号

    NP_001028496

    途径

    Positive Regulation of fat Cell Differentiation
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