ZBTB16 抗体
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北京 101111
Quick Overview for ZBTB16 抗体 (ABIN2668927)
抗原
See all ZBTB16 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PLZF antibody (mAb) (Clone 2A9)
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纯化方法
- Protein G Chromatography
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免疫原
- This PLZF antibody was raised against a recombinant protein corresponding to full-length mouse PLZF with a GST-Tag.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- PBS pH 7.5 containing 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "AP2α controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression." in: Oncogene, Vol. 35, Issue 23, pp. 3016-26, (2016) (PubMed).
: "NRG1 and KITL Signal Downstream of Retinoic Acid in the Germline to Support Soma-Free Syncytial Growth of Differentiating Spermatogonia." in: Cell death discovery, Vol. 1, (2015) (PubMed).
: "Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 19, pp. 10255-60, (1997) (PubMed).
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- ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))
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别名
- PLZF
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背景
- PLZF (Promyelocytic Leukemia Zinc-Finger protein) is a member of the POK (POZ and Krüppel) family of transcriptional repressors. PLZF is expressed in early, but not differentiated, hematopoietic cells, and is required for spermatogonial stem cell maintenance. In addition, PLZF regulates genes involved in cellular proliferation and differentiation (cyclin A2, Myc and Hox genes) and targeted deletion of PLZF in mice results in limb and axial skeleton and limb deformations.
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分子量
- 90 kDa
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基因ID
- 235320
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NCBI登录号
- NP_001028496
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途径
- Positive Regulation of fat Cell Differentiation
抗原
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