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Histone H4 抗体 (H4K31me1)

This 兔 多克隆 antibody specifically detects Histone H4 in WB, IF 和 DB. It exhibits reactivity toward 人.It has been mentioned in 1 publication
产品编号 ABIN2668878
发货至: 中国
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Quick Overview for Histone H4 抗体 (H4K31me1) (ABIN2668878)

抗原

See all Histone H4 (HISTH4) 抗体
Histone H4 (HISTH4)

适用

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宿主

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克隆类型

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多克隆

标记

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This Histone H4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Dot Blot (DB)
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    H4K31me1

    原理

    Histone H4K31me1 antibody (pAb)

    纯化方法

    Unpurified

    免疫原

    This Histone H4 monomethyl Lys31 antibody was raised against a peptide containing monomethyl Lys31 of human histone H4.
  • 应用备注

    WB: 1:500 - 1:2,000 dilution

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Li, Wu, Kim, Zhao, Hearn, Zhang, Meistrich, Mills: "Chd5 orchestrates chromatin remodelling during sperm development." in: Nature communications, Vol. 5, pp. 3812, (2014) (PubMed).

  • 抗原

    Histone H4 (HISTH4)

    别名

    Histone H4

    背景

    Histone H4 is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, it is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, they play a major role in regulating gene expression. The methylation of histones can occur on two different residues: arginine or lysine. Changes in methylation of histone H2B may be involved in heat-shock mechanisms.

    分子量

    8 kDa

    基因ID

    121504

    NCBI登录号

    NP_778224
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