电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Histone H4 抗体

There are 2+ publications for this product available. The 兔 多克隆 anti-Histone H4 antibody is suitable to detect Histone H4 in samples from 人. It has been validated for WB, ChIP 和 ChIP-seq.
产品编号 ABIN2668156
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Histone H4 抗体 (ABIN2668156)

抗原

See all Histone H4 (HISTH4) 抗体
Histone H4 (HISTH4)

适用

  • 473
  • 276
  • 238
  • 19
  • 12
  • 11
  • 10
  • 10
  • 7
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 450
  • 29
  • 1

克隆类型

  • 347
  • 131
  • 2
多克隆

标记

  • 242
  • 27
  • 20
  • 20
  • 20
  • 20
  • 20
  • 20
  • 7
  • 7
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 2
This Histone H4 antibody is un-conjugated

应用范围

  • 332
  • 179
  • 146
  • 102
  • 100
  • 78
  • 56
  • 55
  • 51
  • 43
  • 39
  • 37
  • 26
  • 16
  • 12
  • 8
  • 8
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
  • 原理

    Histone H4 antibody (pAb)

    纯化方法

    Affinity Purified

    免疫原

    This Histone H4 antibody was raised against a peptide corresponding to amino acids 43- 54 of human histone H4.

    亚型

    IgG
  • 应用备注

    ChIP: 2 - 10 µL per ChIP WB*: 1:500 - 1:2,000 dilution *Note: many chromatin-bound proteins are not soluble in a low salt nuclear extract and fractionate to the pellet. Therefore, we recommend a High Salt / Sonication Protocol when preparing nuclear extracts for Western Blot. For Histone H4, we also offer AbFlex Histone H4 Recombinant Antibody (rAb). For details, see Catalog No. 91295.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Wagner, Ciszewski, Kania, Dastych: "Lactate Stimulates IL-4 and IL-13 Production in Activated HuT-78 T Lymphocytes Through a Process That Involves Monocarboxylate Transporters and Protein Hyperacetylation." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 36, Issue 5, pp. 317-27, (2016) (PubMed).

    Wagner, Ciszewski, Kania: "L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation." in: Cell communication and signaling : CCS, Vol. 13, pp. 36, (2015) (PubMed).

  • 抗原

    Histone H4 (HISTH4)

    别名

    Histone H4

    背景

    Histone H4 is one of the core components of the nucleosome, the basic building block of chromatin. Histones are subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, these modifications play a major role in regulating gene expression.

    分子量

    8 kDa

    基因ID

    8363

    NCBI登录号

    NP_778224
You are here: