ASH2L 抗体
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北京 101111
Quick Overview for ASH2L 抗体 (ABIN2668850)
抗原
See all ASH2L 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ASH2L antibody (pAb)
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纯化方法
- Unpurified
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免疫原
- This ASH2L antibody was raised against full-length recombinant human ASH2L protein.
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anti-Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) antibody
ASH2L 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) (AA 493-628) antibodyASH2L 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6F6B9 unconjugated
anti-Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) (AA 1-534) antibodyASH2L 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) antibodyASH2L 适用: 人 WB, ICC, FACS, DB 宿主: 小鼠 Monoclonal 2046D2a unconjugated
anti-Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) (AA 288-337) antibodyASH2L 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 猴, Bat, 兔, Pig, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) antibodyASH2L 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1485 unconjugated Recombinant Antibody
anti-Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) (AA 1-534) antibodyASH2L 适用: 人, 小鼠 WB, IHC, ELISA, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) (AA 347-382) antibodyASH2L 适用: 小鼠 WB 宿主: 兔 Polyclonal RB52789 unconjugated
anti-Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) antibodyASH2L 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) (AA 424-530) antibodyASH2L 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B4 unconjugated
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应用备注
- ChIP: 10 µL per ChIP ChIP-Seq: 10 µL each WB*: 1:500 - 1:2,000 dilution ChIP-Seq validation was performed by Active Motif's Epigenetics Services, the complete data set is available in the UCSC Genome Browser by clicking here. *Note: many chromatin-bound proteins are not soluble in a low salt nuclear extract and fractionate to the pellet. Therefore, we recommend a High Salt / Sonication Protocol when preparing nuclear extracts for Western blot.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "NF-Y recruits Ash2L to impart H3K4 trimethylation on CCAAT promoters." in: PLoS ONE, Vol. 6, Issue 3, pp. e17220, (2011) (PubMed).
: "An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain." in: PLoS ONE, Vol. 5, Issue 11, pp. e14102, (2010) (PubMed).
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- ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))
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别名
- ASH2L
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背景
- ASH2L (absent, small or homeotic discs 2) is a trithorax protein and is a component of different protein complexes, including i.e. mixed-lineage leukemia (MLL) oncoproteins, which contain histone methyltransferase activity. These complexes trimethylate the lysine 4 of histone H3. Histone H3 trimethyl Lys4 is one of histone modifications that are part of elaborate mechanisms that evolved to control the structure of the chromatin.
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分子量
- 77 kDa
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基因ID
- 430
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NCBI登录号
- NP_004665
抗原
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