RBPJ 抗体
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北京 101111
Quick Overview for RBPJ 抗体 (ABIN2668822)
抗原
See all RBPJ 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- RBPJ antibody (mAb) (Clone 1F1)
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纯化方法
- Protein G Chromatography
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免疫原
- This antibody was raised against a full-length recombinant protein corresponding to human RBPJ.
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亚型
- IgG2b
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anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-29), (N-Term) antibody
RBPJ 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB36620 unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 101-200) antibodyRBPJ 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-29) antibodyRBPJ 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (C-Term) antibodyRBPJ 适用: 人, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, 非洲爪蟾, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 3-109) antibodyRBPJ 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-487) antibodyRBPJ 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 243-485) antibodyRBPJ 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-260) antibodyRBPJ 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) antibodyRBPJ 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (C-Term) antibodyRBPJ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- ICC/IF: 0.5 μg/mL dilution
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 41, pp. 13794-807, (2010) (PubMed).
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- RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
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别名
- RBPJ
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背景
- RBPJ (Recombination Signal Binding Protein For Immunoglobulin Kappa J Region) is a transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA.
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分子量
- 68 kDa
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基因ID
- 3516
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NCBI登录号
- NP_056958
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途径
- Notch Signaling, Stem Cell Maintenance, Smooth Muscle Cell Migration
抗原
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