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Retinoic Acid Receptor beta 抗体 (AA 413-448)

Cited in 2+ publications. The 小鼠 单克隆 anti-Retinoic Acid Receptor beta antibody (Clone 8B-10B2) (ABIN2668691) specifically detects Retinoic Acid Receptor beta in WB, IHC 和 SSA. The antibody is reactive with 人 samples.
产品编号 ABIN2668691
发货至: 中国
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Quick Overview for Retinoic Acid Receptor beta 抗体 (AA 413-448) (ABIN2668691)

抗原

See all Retinoic Acid Receptor beta (RARB) 抗体
Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

适用

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宿主

  • 77
  • 8
小鼠

克隆类型

  • 66
  • 19
单克隆

标记

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This Retinoic Acid Receptor beta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Supershift Assay (SSA)

克隆位点

8B-10B2
  • 抗原表位

    • 15
    • 8
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    • 1
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    AA 413-448

    原理

    RAR-beta antibody (mAb) (Clone 8B-10B2)

    纯化方法

    Protein G Chromatography

    免疫原

    This RAR-beta antibody was raised against amino acids 413-448 of human RAR-beta.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Boehm, Samama, Cribier, Rochette-Egly: "Retinoic-acid receptor beta expression in melanocytes." in: European journal of dermatology : EJD, Vol. 14, Issue 1, pp. 19-23, (2004) (PubMed).

    Chakravarti, Mathur, Bahadur, Shukla, Rochette-Egly, Ralhan: "Expression of RARalpha and RARbeta in human oral potentially malignant and neoplastic lesions." in: International journal of cancer. Journal international du cancer, Vol. 91, Issue 1, pp. 27-31, (2001) (PubMed).

  • 抗原

    Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

    别名

    RAR-beta

    背景

    RAR-b (HAP, NR1B2) is a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. RAR-b localizes to the cytoplasm and to subnuclear compartments. RAR-b binds retinoic acid, the biologically active form of vitamin A which mediates cellular signaling in embryonic morphogenesis, cell growth and differentiation. It is thought that RAR-b limits growth of many cell types by regulating gene expression.

    分子量

    50 kDa

    基因ID

    5915

    NCBI登录号

    NP_000956

    途径

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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