Retinoic Acid Receptor beta 抗体 (AA 413-448)
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Quick Overview for Retinoic Acid Receptor beta 抗体 (AA 413-448) (ABIN2668691)
抗原
See all Retinoic Acid Receptor beta (RARB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 413-448
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原理
- RAR-beta antibody (mAb) (Clone 8B-10B2)
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纯化方法
- Protein G Chromatography
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免疫原
- This RAR-beta antibody was raised against amino acids 413-448 of human RAR-beta.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Retinoic-acid receptor beta expression in melanocytes." in: European journal of dermatology : EJD, Vol. 14, Issue 1, pp. 19-23, (2004) (PubMed).
: "Expression of RARalpha and RARbeta in human oral potentially malignant and neoplastic lesions." in: International journal of cancer. Journal international du cancer, Vol. 91, Issue 1, pp. 27-31, (2001) (PubMed).
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- Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
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别名
- RAR-beta
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背景
- RAR-b (HAP, NR1B2) is a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. RAR-b localizes to the cytoplasm and to subnuclear compartments. RAR-b binds retinoic acid, the biologically active form of vitamin A which mediates cellular signaling in embryonic morphogenesis, cell growth and differentiation. It is thought that RAR-b limits growth of many cell types by regulating gene expression.
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分子量
- 50 kDa
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基因ID
- 5915
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NCBI登录号
- NP_000956
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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