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Aurora Kinase B 抗体 (C-Term)

The 兔 多克隆 anti-Aurora Kinase B antibody is suitable to detect Aurora Kinase B in samples from 人 和 小鼠. It has been validated for WB, IF 和 ICC.
产品编号 ABIN2668672
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Aurora Kinase B 抗体 (C-Term) (ABIN2668672)

抗原

See all Aurora Kinase B (AURKB) 抗体
Aurora Kinase B (AURKB)

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Aurora Kinase B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    C-Term

    原理

    Aurora B antibody (pAb)

    纯化方法

    Unpurified

    免疫原

    This Aurora B antibody was raised against a peptide including the C-terminus of human Aurora B.
  • 应用备注

    ICC/IF: 1:200 - 1:1,000 dilution WB: 1:500 - 1:5,000 dilution

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • 抗原

    Aurora Kinase B (AURKB)

    别名

    Aurora B

    背景

    Aurora B (Aurora Kinase B, AurB, ARK2) is a Ser/Thr kinase that is part of the chromosomal passenger complex that associates with chromosomes and is an important regulator of mitosis and meiosis. Aurora B becomes concentrated at the centromere during the onset of mitosis, but relocates to the spindle midzone during anaphase. Aurora B phosphorylates a number of substrates, including INCENP, CENP-A, and Histone H3. Misregulation of Aurora B activity can lead to chromosome instability and is implicated in a number of cancers.

    分子量

    49 kDa

    基因ID

    9212

    NCBI登录号

    NP_004208

    途径

    TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
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