Aurora Kinase B 抗体 (C-Term)
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Quick Overview for Aurora Kinase B 抗体 (C-Term) (ABIN2668672)
抗原
See all Aurora Kinase B (AURKB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Aurora B antibody (pAb)
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纯化方法
- Unpurified
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免疫原
- This Aurora B antibody was raised against a peptide including the C-terminus of human Aurora B.
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应用备注
- ICC/IF: 1:200 - 1:1,000 dilution WB: 1:500 - 1:5,000 dilution
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- Aurora Kinase B (AURKB)
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别名
- Aurora B
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背景
- Aurora B (Aurora Kinase B, AurB, ARK2) is a Ser/Thr kinase that is part of the chromosomal passenger complex that associates with chromosomes and is an important regulator of mitosis and meiosis. Aurora B becomes concentrated at the centromere during the onset of mitosis, but relocates to the spindle midzone during anaphase. Aurora B phosphorylates a number of substrates, including INCENP, CENP-A, and Histone H3. Misregulation of Aurora B activity can lead to chromosome instability and is implicated in a number of cancers.
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分子量
- 49 kDa
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基因ID
- 9212
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NCBI登录号
- NP_004208
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途径
- TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
抗原
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