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Histone H1 抗体

This 兔 多克隆 antibody specifically detects Histone H1 in WB, IF 和 ICC. It exhibits reactivity toward 人. It has been mentioned in 2+ publications
产品编号 ABIN2667975
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Histone H1 抗体 (ABIN2667975)

抗原

See all Histone H1 抗体
Histone H1

适用

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人

宿主

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兔

克隆类型

  • 95
  • 68
多克隆

标记

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This Histone H1 antibody is un-conjugated

应用范围

  • 108
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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 原理

    Histone H1 antibody (pAb)

    纯化方法

    Unpurified

    免疫原

    This Histone H1 antibody was raised against calf thymus histone H1.
  • 应用备注

    ICC/IF: 1:500 - 1:1,000 dilution WB: 1:500 - 1:5,000 dilution

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Li, Wu, Kim, Zhao, Hearn, Zhang, Meistrich, Mills: "Chd5 orchestrates chromatin remodelling during sperm development." in: Nature communications, Vol. 5, pp. 3812, (2014) (PubMed).

    Hagarman, Motley, Kristjansdottir, Soloway: "Coordinate regulation of DNA methylation and H3K27me3 in mouse embryonic stem cells." in: PLoS ONE, Vol. 8, Issue 1, pp. e53880, (2013) (PubMed).

  • 抗原

    Histone H1

    背景

    The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, it is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, they play a major role in regulating gene expression.

    分子量

    31 kDa

    基因ID

    3006

    NCBI登录号

    XP_010816821
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