Rpb1 CTD 抗体 (Tyr1)
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北京 101111
Quick Overview for Rpb1 CTD 抗体 (Tyr1) (ABIN2668519)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Tyr1
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纯化方法
- Protein G Chromatography
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免疫原
- This antibody was raised against a synthetic peptide containing the RNA Pol II heptad repeat consensus sequence phosphorylated at tyrosine 1.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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储存条件
- -20 °C
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储存方法
- Antibodies in solution can be stored at -20 °C for 2 years.
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有效期
- 6 months
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: "Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue." in: Cell reports, Vol. 15, Issue 10, pp. 2147-2158, (2016) (PubMed).
: "CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes." in: Nature structural & molecular biology, Vol. 22, Issue 5, pp. 396-403, (2015) (PubMed).
: "Herpes Simplex Virus 1 (HSV-1) ICP22 protein directly interacts with cyclin-dependent kinase (CDK)9 to inhibit RNA polymerase II transcription elongation." in: PLoS ONE, Vol. 9, Issue 9, pp. e107654, (2014) (PubMed).
: "CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II." in: Science (New York, N.Y.), Vol. 336, Issue 6089, pp. 1723-5, (2012) (PubMed).
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- Rpb1 CTD (RNA Polymerase II CTD)
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别名
- RNA Pol II CTD
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分子量
- 210 kDa
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基因ID
- 5430
抗原
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