HDAC4 抗体 (AA 194-209)
Quick Overview for HDAC4 抗体 (AA 194-209) (ABIN2668313)
抗原
See all HDAC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 194-209
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纯化方法
- Affinity Purified
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免疫原
- This HDAC4 antibody was raised against a synthetic peptide corresponding to amino acid residues 194-209 of human HDAC4.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 μg/μL
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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储存条件
- -80 °C
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储存方法
- Antibodies in solution can be stored at -80 °C for 2 years.
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有效期
- 6 months
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Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." in: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).
: "Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment." in: Cancer research, Vol. 73, Issue 4, pp. 1386-99, (2013) (PubMed).
: "A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression." in: Journal of virology, Vol. 83, Issue 10, pp. 4749-56, (2009) (PubMed).
: "Histone deacetylase 7 silencing alters endothelial cell migration, a key step in angiogenesis." in: Circulation research, Vol. 101, Issue 12, pp. 1237-46, (2007) (PubMed).
: "Estrogen receptor alpha inhibits p53-mediated transcriptional repression: implications for the regulation of apoptosis." in: Cancer research, Vol. 67, Issue 16, pp. 7746-55, (2007) (PubMed).
: "Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63." in: Nucleic acids research, Vol. 34, Issue 3, pp. 928-38, (2006) (PubMed).
: "DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines." in: The Journal of biological chemistry, Vol. 281, Issue 4, pp. 2347-57, (2006) (PubMed).
: "Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters." in: Molecular and cellular biology, Vol. 25, Issue 9, pp. 3737-51, (2005) (PubMed).
: "Dynamic recruitment of NF-Y and histone acetyltransferases on cell-cycle promoters." in: The Journal of biological chemistry, Vol. 278, Issue 33, pp. 30435-40, (2003) (PubMed).
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Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." in: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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别名
- HDAC4
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分子量
- 140 kDa
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基因ID
- 9759
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
抗原
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