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HDAC4 抗体 (AA 194-209)

This anti-HDAC4 antibody is a 兔 多克隆 antibody detecting HDAC4 in WB, ChIP 和 ChIP-seq. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 9+ publications.
产品编号 ABIN2668313
发货至: 中国

Quick Overview for HDAC4 抗体 (AA 194-209) (ABIN2668313)

抗原

See all HDAC4 抗体
HDAC4 (Histone Deacetylase 4 (HDAC4))

适用

  • 120
  • 49
  • 34
  • 6
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 109
  • 15
  • 1

克隆类型

  • 106
  • 19
多克隆

标记

  • 74
  • 8
  • 7
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HDAC4 antibody is un-conjugated

应用范围

  • 86
  • 48
  • 29
  • 24
  • 20
  • 15
  • 14
  • 14
  • 11
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
  • 抗原表位

    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 194-209

    纯化方法

    Affinity Purified

    免疫原

    This HDAC4 antibody was raised against a synthetic peptide corresponding to amino acid residues 194-209 of human HDAC4.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 μg/μL

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    储存条件

    -80 °C

    储存方法

    Antibodies in solution can be stored at -80 °C for 2 years.

    有效期

    6 months
  • Liu, Gu, Feng, Yang, Zhu, Lu, Qi: "Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." in: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).

    Isaacs, Antony, Dalrymple, Brennen, Gerber, Hammers, Wissing, Kachhap, Luo, Xing, Björk, Olsson, Björk, Leanderson: "Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment." in: Cancer research, Vol. 73, Issue 4, pp. 1386-99, (2013) (PubMed).

    Keedy, Archin, Gates, Espeseth, Hazuda, Margolis: "A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression." in: Journal of virology, Vol. 83, Issue 10, pp. 4749-56, (2009) (PubMed).

    Mottet, Bellahcène, Pirotte, Waltregny, Deroanne, Lamour, Lidereau, Castronovo: "Histone deacetylase 7 silencing alters endothelial cell migration, a key step in angiogenesis." in: Circulation research, Vol. 101, Issue 12, pp. 1237-46, (2007) (PubMed).

    Sayeed, Konduri, Liu, Bansal, Li, Das: "Estrogen receptor alpha inhibits p53-mediated transcriptional repression: implications for the regulation of apoptosis." in: Cancer research, Vol. 67, Issue 16, pp. 7746-55, (2007) (PubMed).

    Testoni, Mantovani: "Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63." in: Nucleic acids research, Vol. 34, Issue 3, pp. 928-38, (2006) (PubMed).

    Basile, Mantovani, Imbriano: "DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines." in: The Journal of biological chemistry, Vol. 281, Issue 4, pp. 2347-57, (2006) (PubMed).

    Imbriano, Gurtner, Cocchiarella, Di Agostino, Basile, Gostissa, Dobbelstein, Del Sal, Piaggio, Mantovani: "Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters." in: Molecular and cellular biology, Vol. 25, Issue 9, pp. 3737-51, (2005) (PubMed).

    Caretti, Salsi, Vecchi, Imbriano, Mantovani: "Dynamic recruitment of NF-Y and histone acetyltransferases on cell-cycle promoters." in: The Journal of biological chemistry, Vol. 278, Issue 33, pp. 30435-40, (2003) (PubMed).

  • 抗原

    HDAC4 (Histone Deacetylase 4 (HDAC4))

    别名

    HDAC4

    分子量

    140 kDa

    基因ID

    9759

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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