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CD8 抗体

CD8 适用: Marmoset FACS, IF 宿主: 小鼠 Monoclonal 6F10 unconjugated
产品编号 ABIN2667342
发货至: 中国
  • 抗原 See all CD8 抗体
    CD8
    适用
    • 197
    • 66
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    Marmoset
    宿主
    • 229
    • 48
    • 36
    • 4
    小鼠
    克隆类型
    • 280
    • 30
    • 2
    单克隆
    标记
    • 102
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    This CD8 antibody is un-conjugated
    应用范围
    • 279
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    交叉反应
    Squirrel Monkey (Saimiri spec.)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    6F10
    亚型
    IgG1
    Top Product
    Discover our top product CD8 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD8
    别名
    CD8 (CD8 产品)
    背景
    CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
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