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c-MYC 抗体

MYC 适用: 人 FACS 宿主: 小鼠 Monoclonal 9E10 unconjugated
产品编号 ABIN2666320
发货至: 中国
  • 抗原 See all c-MYC (MYC) 抗体
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This c-MYC antibody is un-conjugated
    应用范围
    • 289
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    Flow Cytometry (FACS)
    交叉反应 (详细)
    Fusion protein in all species
    产品特性
    The c-myc protein is a 62 kD nuclear factor that is ubiquitously expressed in the nucleus. c-myc is part of a heterodimeric complex with MAX that acts as a potent transcriptional activator. c-myc is modified by glycosylation and phosphorylation and has been shown to interact with a number of proteins including SMAD2, SMAD3, Pam, cdc6, BRCA1, Mlh1, p34cdc2, MAD, and Sp1. c-myc is extremely labile and is degraded very quickly even in extracts prepared with boiling SDS sample buffer, such that the observed protein size is approximately 41 kD. The 9E10 monoclonal antibody recognizes human myc and the 10 amino acid epitope tag of human c-myc. The 9E10 antibody has been shown to be useful in a number of applications including Western blotting, direct ELISA, flow cytometry, immunoprecipitation, immunofluorescence, immunohistochemistry (paraffin), and immunoaffinity purification of proteins expressing the human c-myc tag.
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    9E10
    亚型
    IgG1, IgG1 kappa
    Top Product
    Discover our top product MYC Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Upon receipt, store undiluted between 2°C and 8°C.
  • 抗原
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    别名
    C-Myc (MYC 产品)
    途径
    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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